Literature DB >> 1365664

Role of central ATP-sensitive potassium channels in the hyperthermic effect of morphine in mice.

M Narita1, T Suzuki, M Misawa, H Nagase.   

Abstract

Morphine (10 mg/kg, SC) in combination with ICV vehicle induced a significant hyperthermic effect at 120 min (peak time) after injection compared to ICV vehicle plus SC saline (control group). Glibenclamide (50 micrograms, ICV), a selective adenosine triphosphate-sensitive potassium (KATP) channel blocker, in combination with SC saline hardly affected the rectal temperature compared to the control group. ICV glibenclamide antagonized the hyperthermia induced by SC morphine in a dose-dependent manner. From these results, we demonstrated that KATP channels play an important role as modulators of the hyperthermic effect of mu agonists.

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Year:  1992        PMID： 1365664     DOI： 10.1007/bf02245507

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  10 in total

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Authors:  T J HALEY; W G MCCORMICK
Journal:  Br J Pharmacol Chemother       Date:  1957-03

2.  An ATP-dependent potassium channel blocker antagonizes morphine analgesia.

Authors:  M Ocaña; E Del Pozo; M Barrios; L I Robles; J M Baeyens
Journal:  Eur J Pharmacol       Date:  1990-09-21       Impact factor: 4.432

3.  Opioid delta receptor subtypes are associated with different potassium channels.

Authors:  K D Wild; T Vanderah; H I Mosberg; F Porreca
Journal:  Eur J Pharmacol       Date:  1991-01-25       Impact factor: 4.432

4.  Alteration of thermoregulatory set point with opioid agonists.

Authors:  R L Spencer; V J Hruby; T F Burks
Journal:  J Pharmacol Exp Ther       Date:  1990-02       Impact factor: 4.030

5.  Sulfonylurea binding sites associated with ATP-regulated K+ channels in the central nervous system: autoradiographic analysis of their distribution and ontogenesis, and of their localization in mutant mice cerebellum.

Authors:  C Mourre; C Widmann; M Lazdunski
Journal:  Brain Res       Date:  1990-06-11       Impact factor: 3.252

6.  Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration.

Authors:  M A Werz; R L Macdonald
Journal:  J Pharmacol Exp Ther       Date:  1985-07       Impact factor: 4.030

7.  Intracellular ATP directly blocks K+ channels in pancreatic B-cells.

Authors:  D L Cook; C N Hales
Journal:  Nature       Date:  1984 Sep 20-26       Impact factor: 49.962

8.  Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance.

Authors:  M A Werz; R L MacDonald
Journal:  Neurosci Lett       Date:  1983-12-02       Impact factor: 3.046

9.  Subclasses of opioids based on body temperature change in rats: acute subcutaneous administration.

Authors:  E B Geller; C Hawk; S H Keinath; R J Tallarida; M W Adler
Journal:  J Pharmacol Exp Ther       Date:  1983-05       Impact factor: 4.030

10.  Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels.

Authors:  S Amoroso; H Schmid-Antomarchi; M Fosset; M Lazdunski
Journal:  Science       Date:  1990-02-16       Impact factor: 47.728
  10 in total
  4 in total

1.  An ATP-sensitive potassium channel blocker abolishes the potentiating effect of morphine on the bicuculline-induced convulsion in mice.

Authors:  M Narita; Y Takahashi; T Suzuki; M Misawa; H Nagase
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

2.  Opioid receptors and myocardial protection: do opioid agonists possess cardioprotective effects?

Authors:  K J McCormack; C B Chapleo
Journal:  Clin Drug Investig       Date:  1998       Impact factor: 2.859

3.  Subgroups among mu-opioid receptor agonists distinguished by ATP-sensitive K+ channel-acting drugs.

Authors:  M Ocaña; E Del Pozo; M Barrios; J M Baeyens
Journal:  Br J Pharmacol       Date:  1995-03       Impact factor: 8.739

4.  Activation of central ATP-sensitive potassium channels produces the antinociception and spinal noradrenaline turnover-enhancing effect in mice.

Authors:  M Narita; K Takamori; N Kawashima; M Funada; J Kamei; T Suzuki; M Misawa; H Nagase
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530
  4 in total

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