Literature DB >> 1364819

Coronary vasoconstriction in the conscious rabbit following intravenous infusion of L-NG-nitro-arginine.

R G Humphries1, R D Carr, A K Nicol, W Tomlinson, S E O'Connor.   

Abstract

Intravenous infusion of L-NG-nitro-arginine, an inhibitor of endothelial nitric oxide (NO) synthesis, produced vasoconstriction in the coronary, cerebral, renal and duodenal vascular beds of the conscious rabbit. In this study, using radiolabelled microspheres, we provide in vivo evidence for a basal NO-dependent vasodilator tone in the coronary vascular bed.

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Year:  1991        PMID： 1364819      PMCID： PMC1917934          DOI： 10.1111/j.1476-5381.1991.tb12212.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  Blood flow measurements with radionuclide-labeled particles.

Authors:  M A Heymann; B D Payne; J I Hoffman; A M Rudolph
Journal:  Prog Cardiovasc Dis       Date:  1977 Jul-Aug       Impact factor: 8.194

2.  Platelets, endothelium, and vasospasm.

Authors:  P M Vanhoutte; D S Houston
Journal:  Circulation       Date:  1985-10       Impact factor: 29.690

3.  Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide.

Authors:  C Boulanger; V B Schini; S Moncada; P M Vanhoutte
Journal:  Br J Pharmacol       Date:  1990-09       Impact factor: 8.739

4.  Control of regional blood flow by endothelium-derived nitric oxide.

Authors:  S M Gardiner; A M Compton; T Bennett; R M Palmer; S Moncada
Journal:  Hypertension       Date:  1990-05       Impact factor: 10.190

5.  Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs.

Authors:  A Chu; D E Chambers; C C Lin; W D Kuehl; F R Cobb
Journal:  Am J Physiol       Date:  1990-04

6.  L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro.

Authors:  P K Moore; O A al-Swayeh; N W Chong; R A Evans; A Gibson
Journal:  Br J Pharmacol       Date:  1990-02       Impact factor: 8.739

7.  Role of endothelium-derived nitric oxide in the regulation of blood pressure.

Authors:  D D Rees; R M Palmer; S Moncada
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

8.  Calcium antagonist and the peripheral circulation: differences and similarities between PY 108-068, nicardipine, verapamil and diltiazem.

Authors:  R P Hof
Journal:  Br J Pharmacol       Date:  1983-02       Impact factor: 8.739

9.  Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit.

Authors:  J L Amezcua; R M Palmer; B M de Souza; S Moncada
Journal:  Br J Pharmacol       Date:  1989-08       Impact factor: 8.739
  9 in total
  9 in total

1.  The influence of atropine and atenolol on the cardiac haemodynamic effects of NG-nitro-L-arginine methyl ester in conscious, Long Evans rats.

Authors:  R E Widdop; S M Gardiner; P A Kemp; T Bennett
Journal:  Br J Pharmacol       Date:  1992-03       Impact factor: 8.739

2.  Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock.

Authors:  C Szabó; J A Mitchell; C Thiemermann; J R Vane
Journal:  Br J Pharmacol       Date:  1993-03       Impact factor: 8.739

3.  Regional coronary haemodynamic effects of two inhibitors of nitric oxide synthesis in anaesthetized, open-chest dogs.

Authors:  V Richard; A Berdeaux; C D la Rochelle; J F Giudicelli
Journal:  Br J Pharmacol       Date:  1991-09       Impact factor: 8.739

4.  Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat.

Authors:  A G Kovách; C Szabó; Z Benyó; C Csáki; J H Greenberg; M Reivich
Journal:  J Physiol       Date:  1992-04       Impact factor: 5.182

5.  NG-nitro L-arginine methyl ester: systemic and pulmonary haemodynamics, tissue blood flow and arteriovenous shunting in the pig.

Authors:  E M van Gelderen; M O Den Boer; P R Saxena
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-10       Impact factor: 3.000

6.  Nitric oxide modulates vascular permeability in the rat coronary circulation.

Authors:  J G Filep; E Földes-Filep; P Sirois
Journal:  Br J Pharmacol       Date:  1993-02       Impact factor: 8.739

7.  Haemodynamic changes and acetylcholine-induced hypotensive responses after NG-nitro-L-arginine methyl ester in rats and cats.

Authors:  E Marcel van Gelderen; J P Heiligers; P R Saxena
Journal:  Br J Pharmacol       Date:  1991-08       Impact factor: 8.739

8.  A comparison of the inhibitory effects of sodium nitroprusside, pinacidil and nifedipine on pressor response to NG-nitro-L-arginine.

Authors:  Y X Wang; T Zhou; C C Pang
Journal:  Br J Pharmacol       Date:  1993-02       Impact factor: 8.739

9.  Enhancement of noradrenergic constriction of large coronary arteries by inhibition of nitric oxide synthesis in anaesthetized dogs.

Authors:  O L Woodman; P Pannangpetch
Journal:  Br J Pharmacol       Date:  1994-06       Impact factor: 8.739
  9 in total

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