Literature DB >> 13646630

Interference with feedback control; a mechanism of antimetabolite action.

H S MOYED, M FRIEDMAN.   

Abstract

The action of an enzyme essential for tryptophan biosynthesis is inhibited by tryptophan and also by an analog of tryptophan. Similarly, histidine and one of its analogs inhibit the action of an enzyme essential for histidine biosynthesis. A mutant resistant to the histidine analog produces an apparently altered enzyme which is insensitive to both the analog and histidine.

Entities:  

Keywords:  HISTIDINE/metabolism; TRYPTOPHAN/metabolism

Mesh：

Substances：

Year:  1959        PMID： 13646630     DOI： 10.1126/science.129.3354.968

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

1.  The effect of amino acid analogues on growth and protein synthesis in microorganisms.

Authors:  M H RICHMOND
Journal:  Bacteriol Rev       Date:  1962-12

2.  The tryptophan synthetase system.

Authors:  C YANOFSKY
Journal:  Bacteriol Rev       Date:  1960-06

3.  Influence of 3-methylanthranilic and anthranilic acids on the formation of tryptophan synthetase in Escherichia coli.

Authors:  G LESTER; C YANOFSKY
Journal:  J Bacteriol       Date:  1961-01       Impact factor: 3.490

4.  COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE.

Authors:  B N Ames; B Garry
Journal:  Proc Natl Acad Sci U S A       Date:  1959-10       Impact factor: 11.205

5.  Reduction of radiation damage to Tradescantia chromosomes by adenosine triphosphate, proline, and histidine.

Authors:  A V Beatty; J W Beatty
Journal:  Genetics       Date:  1966-01       Impact factor: 4.562

6.  Histidine production by a regulatory mutant of Streptomyces coelicolor.

Authors:  V Derkos-Sojak; J Korajlija; V Delíc
Journal:  Appl Environ Microbiol       Date:  1977-12       Impact factor: 4.792

7.  Inhibition of growth of Escherichia coli and of homoserine O-transsuccinylase by alpha-methylmethionine.

Authors:  S Schlesinger
Journal:  J Bacteriol       Date:  1967-08       Impact factor: 3.490

8.  Repression and inhibition of indole-synthesizing activity in Neurospora crassa.

Authors:  G LESTER
Journal:  J Bacteriol       Date:  1961-08       Impact factor: 3.490

9.  Anthranilate synthase-anthranilate 5-phosphoribosyl 1-pyrophosphate phosphoribosyltransferase from Aerobacter aerogenes.

Authors:  A F Egan; F Gibson
Journal:  Biochem J       Date:  1972-12       Impact factor: 3.857

10.  Glycerol kinase, the pacemaker for the dissimilation of glycerol in Escherichia coli.

Authors:  N Zwaig; W S Kistler; E C Lin
Journal:  J Bacteriol       Date:  1970-06       Impact factor: 3.490
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.