| Literature DB >> 13635024 |
A PLETSCHER, H BESENDORF, K F GEY.
Abstract
The effects of two benzoquinolizine derivatives on the 5-hydroxytryptamine and norepinephrine content of the brain of mice, and some pharmacological actions, are described. Certain central effects (such as sedation and narcosis potentiation) of benzoquinolizine derivatives and possibly of Rauwolfia alkaloids may be due to changes of norepinephrine metabolism rather than to changes of 5-hydroxytryptamine metabolism in the brain.Entities:
Keywords: ARTERENOL/metabolism; BRAIN/metabolism; HETEROCYCLIC COMPOUNDS/effects; SEROTONIN/metabolism
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Year: 1959 PMID： 13635024 DOI： 10.1126/science.129.3352.844
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728