Literature DB >> 13635009

New method for the rapid determination of lathyrogenic agents.

B M LEVY.   

Abstract

Salamander and toad embryos will develop grossly observable tumors of the notochord if they are placed for 3 or more days in a solution of the lathyrism-producing chemicals beta-aminopropionitrile or aminoacetonitrile. A technique for using tumorigenesis in amphibian embryos as a biological indicator for other lathyrogenic agents is presented.

Entities:  

Keywords:  LATHYRISM/diagnosis

Mesh:

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Year:  1959        PMID: 13635009     DOI: 10.1126/science.129.3350.720

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Succinic dehydrogenase of weanling normal and osteolathyritic rats.

Authors:  C H WYNN; J BALL
Journal:  Br J Exp Pathol       Date:  1961-04

2.  Influence of D-penicillamine and beta-aminopropionitril on the metamorphosis of Rana temporaria.

Authors:  L Friedrich; D Wuppermann; F Zimmermann
Journal:  Arch Toxicol       Date:  1976-06-08       Impact factor: 5.153

  2 in total

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