Literature DB >> 1362974

[Role of glutamate intracortical connections in conditioned reflex activity].

V M Storozhuk, S F Ivanova, A V Sanzharovskiĭ.   

Abstract

The effects of iontophoretic application of glutamate and its blockers on neuronal activity of the sensorimotor cortex were studied in cat during fulfillment of conditioned instrumental placing reflex. 64 neurons were investigated. Application of glutamate caused reliable facilitation of neuronal impulse reactions to the conditioned stimulus. The facilitation appeared some seconds after beginning of the application of glutamate and continued for 5-10 min after cessation of the iontophoretic application. The similar inhibitory effect in neuronal activity was observed with application of APV, kinurenate, ketamine. It is suggested that the NMDA receptors under natural conditions take part in facilitation of the synaptic transmission in glutamatergic intracortical pathways.

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Year:  1992        PMID： 1362974

Source DB:  PubMed          Journal:  Neirofiziologiia        ISSN： 0028-2561


  9 in total

1.  Modulation of the spike activity of neocortex neurons during a conditioned reflex.

Authors:  V M Storozhuk; A V Sanzharovskii; V V Sachenko; B I Busel
Journal:  Neurosci Behav Physiol       Date:  2000 Nov-Dec

2.  The effects of an NDMA receptor antagonist on delayed visual differentiation in monkeys and rearrangements of neuron spike activity in the visual and prefrontal areas of the cortex.

Authors:  K N Dudkin; V K Kruchinin; I V Chueva
Journal:  Neurosci Behav Physiol       Date:  2001 Mar-Apr

3.  Neurophysiological correlates of delayed visual differentiation tasks in monkeys: the effects of the site of intracortical blockade of NMDA receptors.

Authors:  K N Dudkin; V K Kruchinin; I V Chueva
Journal:  Neurosci Behav Physiol       Date:  2001 Mar-Apr

4.  Organization of working memory processes in monkeys: the effects of a dopamine receptor agonist.

Authors:  K N Dudkin; I V Chueva; M U Arinbasarov; N V Bobkova
Journal:  Neurosci Behav Physiol       Date:  2003-05

5.  Effect of 2-amino-5-phosphopentanoic acid (AP5), a glutamate NMDA receptor blocker, on neuron activity in the cat motor cortex during performance of a paw placement conditioned reflex.

Authors:  V I Maiorov; B V Chernyshev; A A Moskvitin
Journal:  Neurosci Behav Physiol       Date:  1998 Sep-Oct

6.  Cholinergic dependence of a cortical neuronal mechanism that supports Pavlovian eyeblink conditioning.

Authors:  N Jahed; E Gruen; C D Woody
Journal:  Neurosci Behav Physiol       Date:  1997 Sep-Oct

7.  Neurophysiological correlates of improvements in cognitive characteristics in monkeys during modification of NMDA-ergic structures of the prefrontal cortex.

Authors:  K N Dudkin; V K Kruchinin; I V Chueva
Journal:  Neurosci Behav Physiol       Date:  1996 Nov-Dec

8.  Effect of NMDA on the activity of cortical glutaminergic structures in delayed visual differentiation in monkeys.

Authors:  K N Dudkin; V K Kruchinin; I V Chueva
Journal:  Neurosci Behav Physiol       Date:  1997 Mar-Apr

9.  Synchronization processes in the mechanisms of short-term memory in monkeys: the involvement of cholinergic and glutaminergic cortical structures.

Authors:  K N Dudkin; V K Kruchinin; I V Chueva
Journal:  Neurosci Behav Physiol       Date:  1997 May-Jun
  9 in total

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