Literature DB >> 1362561

Detection of a new polymorphism of the human prothrombin (F2) gene by combination of PASA and mutated primer-mediated PCR-RFLP.

H Iwahana1, N Mizusawa, K Yoshimoto, M Itakura.   

Abstract

A new polymorphism of the human prothrombin (F2) gene was detected by a combination of polymerase chain reaction (PCR) amplification of specific alleles (PASA) and mutated primer-mediated PCR restriction fragment length polymorphism (PCR-RFLP). The method is simple and useful for detecting polymorphisms and mutations. The new polymorphism of C1 and C2 examined by this method is highly heterozygous and serves as a good human DNA marker.

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Year:  1992        PMID： 1362561     DOI： 10.1007/bf00220094

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  10 in total

1.  Highly polymorphic region of the human prothrombin (F2) gene.

Authors:  H Iwahana; K Yoshimoto; M Itakura
Journal:  Hum Genet       Date:  1992-04       Impact factor: 4.132

2.  Targeted gene walking polymerase chain reaction.

Authors:  J D Parker; P S Rabinovitch; G C Burmer
Journal:  Nucleic Acids Res       Date:  1991-06-11       Impact factor: 16.971

3.  Polymorphism detected by multiple RENS in the human coagulation factor II (F2) gene.

Authors:  P J McAlpine; M Dickson; C Guy; A Wiens; D M Irwin; R T MacGillivray
Journal:  Nucleic Acids Res       Date:  1991-01-11       Impact factor: 16.971

4.  NcoI RFLP in the human prothrombin (F2) gene.

Authors:  H Iwahana; K Yoshimoto; M Itakura
Journal:  Nucleic Acids Res       Date:  1991-08-11       Impact factor: 16.971

5.  Approach to identification of a point mutation in apo B100 gene by means of a PCR-mediated site-directed mutagenesis.

Authors:  E I Schwartz; S P Shevtsov; A P Kuchinski; O V Plutalov
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

6.  RFLP for the human prothrombin (F2) gene.

Authors:  M de Vetten; H K Ploos van Amstel; P H Reitsma
Journal:  Nucleic Acids Res       Date:  1990-10-11       Impact factor: 16.971

7.  Characterization of polymerase chain reaction amplification of specific alleles.

Authors:  G Sarkar; J Cassady; C D Bottema; S S Sommer
Journal:  Anal Biochem       Date:  1990-04       Impact factor: 3.365

8.  Nucleotide sequence of the gene for human prothrombin.

Authors:  S J Degen; E W Davie
Journal:  Biochemistry       Date:  1987-09-22       Impact factor: 3.162

9.  Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin.

Authors:  S J Degen; R T MacGillivray; E W Davie
Journal:  Biochemistry       Date:  1983-04-26       Impact factor: 3.162

10.  Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively.

Authors:  N J Royle; D M Irwin; M L Koschinsky; R T MacGillivray; J L Hamerton
Journal:  Somat Cell Mol Genet       Date:  1987-05
  10 in total

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