| Literature DB >> 13624720 |
S SANO, S INOUE, Y TANABE, C SUMIYA, S KOIKE.
Abstract
It is concluded that mitochondria are involved in three steps of porphyrin and heme biosynthesis-first, in the formation of delta-aminolevulinic acid from glycine and active succinate; second, in the synthesis of protoporphyrin; third, in the incorporation of iron into the porphyrin ring-that is, in heme formation.Entities:
Keywords: HEMOGLOBIN; MITOCHONDRIA/metabolism; PORPHYRINS/metabolism
Mesh:
Substances:
Year: 1959 PMID: 13624720 DOI: 10.1126/science.129.3344.275
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728