Literature DB >> 1362359

Nitric oxide mediated formation of cyclic GMP in the olfactory system.

H Breer1, T Klemm, I Boekhoff.   

Abstract

Olfactory cilia preparation from rats contain considerable activity of soluble guanylate cyclase as indicated by the formation of cyclic GMP (cGMP) upon application of nitroprusside, a nitric oxide generating agent. Stimulation of olfactory cilia with high doses of odorants elicited a delayed and sustained elevation of the cGMP-concentration. The odorant-induced cGMP-response was abolished by L-NG-nitro-arginine, a selective inhibitor of nitric oxide synthesis, as well as by haemoglobin which efficiently binds and inactivates nitric oxide. These observations suggest that the NO/cGMP cascade may plan an important role in signal processing of the olfactory system.

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Year:  1992        PMID： 1362359     DOI： 10.1097/00001756-199211000-00022

Source DB:  PubMed          Journal:  Neuroreport        ISSN： 0959-4965            Impact factor:   1.837


  12 in total

1.  Calcium entry through cyclic nucleotide-gated channels in individual cilia of olfactory receptor cells: spatiotemporal dynamics.

Authors:  T Leinders-Zufall; M N Rand; G M Shepherd; C A Greer; F Zufall
Journal:  J Neurosci       Date:  1997-06-01       Impact factor: 6.167

2.  Odorants induce the phosphorylation of the cAMP response element binding protein in olfactory receptor neurons.

Authors:  C Moon; Y K Sung; R Reddy; G V Ronnett
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

3.  Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons.

Authors:  C Moon; P Jaberi; A Otto-Bruc; W Baehr; K Palczewski; G V Ronnett
Journal:  J Neurosci       Date:  1998-05-01       Impact factor: 6.167

4.  Identification of a long-lasting form of odor adaptation that depends on the carbon Monoxide/cGMP second-messenger system.

Authors:  F Zufall; T Leinders-Zufall
Journal:  J Neurosci       Date:  1997-04-15       Impact factor: 6.167

5.  Presence of long-lasting peripheral adaptation in oblique-banded leafroller, Choristoneura rosaceana and absence of such adaptation in redbanded leafroller, Argyrotaenia velutinana.

Authors:  Lukasz L Stelinski; James R Miller; Larry J Gut
Journal:  J Chem Ecol       Date:  2003-02       Impact factor: 2.626

6.  Amiloride-insensitive cation conductance in Xenopus laevis olfactory neurons: a combined patch clamp and calcium imaging analysis.

Authors:  D Schild; F W Lischka
Journal:  Biophys J       Date:  1994-02       Impact factor: 4.033

Review 7.  HSV-1 brain infection by the olfactory nerve route and virus latency and reactivation may cause learning and behavioral deficiencies and violence in children and adults: a point of view.

Authors:  Y Becker
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

8.  Inositol-trisphosphate-dependent calcium currents precede cation currents in insect olfactory receptor neurons in vitro.

Authors:  M Stengl
Journal:  J Comp Physiol A       Date:  1994-02       Impact factor: 1.836

9.  Molecular and neuronal homology between the olfactory systems of zebrafish and mouse.

Authors:  Luis R Saraiva; Gaurav Ahuja; Ivan Ivandic; Adnan S Syed; John C Marioni; Sigrun I Korsching; Darren W Logan
Journal:  Sci Rep       Date:  2015-06-25       Impact factor: 4.379

10.  Odorant-dependent generation of nitric oxide in Mammalian olfactory sensory neurons.

Authors:  Daniela Brunert; Stefan Kurtenbach; Sonnur Isik; Heike Benecke; Günter Gisselmann; Wolfgang Schuhmann; Hanns Hatt; Christian H Wetzel
Journal:  PLoS One       Date:  2009-05-11       Impact factor: 3.240
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