Literature DB >> 13618555

The peripheral action of hexamethonium and of pentolinium.

P MANTEGAZZA, C TYLER, K ZAIMIS.   

Abstract

The influence of hexamethonium and pentolinium on the responses of certain peripheral effector cells to adrenaline, noradrenaline or postganglionic stimulation was studied in the cat. The actions of adrenaline and noradrenaline on the blood vessels of a limb and of adrenaline and postganglionic stimulation on the nictitating membrane were increased after the administration of hexamethonium and pentolinium. This effect was considered to be due to sensitization of the peripheral effector cells. The possible significance of these findings is discussed.

Entities:  

Keywords:  ARTERENOL/effects; EPINEPHRINE/effects; HEXAMETHONIUM COMPOUNDS/effects; MUSCLE RELAXANTS/effects; NERVES, PERIPHERAL/effect of drugs on

Mesh:

Substances:

Year:  1958        PMID: 13618555      PMCID: PMC1481890          DOI: 10.1111/j.1476-5381.1958.tb00242.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  8 in total

1.  Correlation between membrane potential, spike discharge and tension in smooth muscle.

Authors:  E BULBRING
Journal:  J Physiol       Date:  1955-04-28       Impact factor: 5.182

2.  [Classification of a group of serotonin antagonists, and analysis of the sites of the peripheral vascular action of serotonin].

Authors:  R MEIER; J TRIPOD; E WIRZ
Journal:  Arch Int Pharmacodyn Ther       Date:  1957-01-01

3.  Role of buffer mechanisms in sympathetic drug action.

Authors:  G D MAENGWYN-DAVIES; D T WALZ; T KOPPANYI
Journal:  Arch Int Pharmacodyn Ther       Date:  1958-01-01

4.  The interruption of ganglionic transmission and some of its problems.

Authors:  E ZAIMIS
Journal:  J Pharm Pharmacol       Date:  1955-08       Impact factor: 3.765

5.  Peripheral action of the ganglion blocking agents.

Authors:  K SHIMAMOTO; O KANAUCHI; S UCHIZUMI
Journal:  Jpn J Pharmacol       Date:  1955-09

6.  The relative effects of ganglion-blocking compounds on the sympathetic and parasympathetic ganglia supplying the cat heart.

Authors:  W L PERRY; C W WILSON
Journal:  Br J Pharmacol Chemother       Date:  1956-03

7.  Potentiation of the pressor action of noradrenaline by hexamethonium, tetraethylammonium, and methantheline.

Authors:  C BARTORELLI; A CARPI; L CAVALCA
Journal:  Br J Pharmacol Chemother       Date:  1954-12

8.  [Potentiation by ganglion-blocking agents of the pressor response to adrenalin and acetylcholine].

Authors:  G SALERNO
Journal:  Rass Int Clin Ter       Date:  1955-04-30
  8 in total
  5 in total

1.  Effect of hexamethonium on the vascular response to noradrenaline in man.

Authors:  R L HODGE; R F WHELAN
Journal:  Br J Pharmacol Chemother       Date:  1962-04

2.  Potentiation of inhibitory and excitatory effects of catechol amines by bretylium.

Authors:  S D GOKHALE; O D GULATI
Journal:  Br J Pharmacol Chemother       Date:  1961-06

3.  Peripheral actions of hexamethonium in relation to the decreasing effects of repeated doses on the blood pressure of anaesthetized rats.

Authors:  J G Blackman; R Laverty
Journal:  Br J Pharmacol Chemother       Date:  1961-08

4.  Relation in rat hind-limb blood vessels between nervous vasomotor tone and the response to vasoconstrictor drugs.

Authors:  R LAVERTY
Journal:  Br J Pharmacol Chemother       Date:  1962-06

5.  THE EFFECTS OF PHYSOSTIGMINE ON THE MECHANICAL AND ELECTRICAL RESPONSES OF THE CAT NICTATING MEMBRANE.

Authors:  W C BOWMAN; B A CALLINGHAM; A W CUTHBERT
Journal:  Br J Pharmacol Chemother       Date:  1964-06
  5 in total

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