| Literature DB >> 1361287 |
A Torrelo1, A Harto, E Sendagorta, B M Czarnetzki, A Ledo.
Abstract
Thirteen patients with a severe adult form of atopic dermatitis (AD) received 3.0 x 10(6) IU of recombinant interferon-alpha 2a (rIFN-alpha 2a) 3 times a week. A satisfactory response was obtained in 5 of them. Serum IgE levels in all 13 patients remained unchanged throughout the study. Flu-like symptoms were common, but clinical or laboratory adverse effects were otherwise slight. The moderately beneficial therapeutic effects observed in this study support a possible role for IFN-alpha in controlling immunologic deficiencies in atopic dermatitis.Entities:
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Year: 1992 PMID： 1361287 DOI： 101080/000155572370372
Source DB: PubMed Journal: Acta Derm Venereol ISSN： 0001-5555 Impact factor: 4.437