Literature DB >> 1360912

The role of prophylactic oophorectomy in the avoidance of ovarian cancer.

P E Schwartz1.   

Abstract

OBJECTIVE: To determine the role of prophylactic oophorectomy at elective hysterectomy in the avoidance of ovarian cancer.
METHOD: A survey was performed of all members of the Society of Gynecologic Oncologists and all obstetrician-gynecologists in the State of Connecticut. RESULT: Seventy-nine percent of gynecologic oncologists and 72% of obstetrician-gynecologists surveyed reported 0-1% of women would be saved from ovarian cancer if one ovary was removed at elective hysterectomy at age 45 years. If both ovaries were removed, 8.4% and 32.1% of these physicians respectively responded that 95-100% of women could be saved from ovarian cancer. Approximately 50% responded that macroscopic appearance and frozen section studies at surgery were helpful in deciding whether to remove ovaries at hysterectomy. A literature review suggested that 12% of ovarian cancers might be avoided if women undergo prophylactic oophorectomy at elective hysterectomy.
CONCLUSION: There is a lack of well-designed epidemiologic studies evaluating risk factors for ovarian cancer and the role of prophylactic oophorectomy at elective hysterectomy.

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Year:  1992        PMID: 1360912     DOI: 10.1016/0020-7292(92)90655-3

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  2 in total

1.  Fallopian tube as main source for ovarian and pelvic (non-endometrial) serous carcinomas.

Authors:  Wenxin Zheng; Oluwole Fadare
Journal:  Int J Clin Exp Pathol       Date:  2012-03-25

Review 2.  Oophorectomy: the debate between ovarian conservation and elective oophorectomy.

Authors:  Elisabeth A Erekson; Deanna K Martin; Elena S Ratner
Journal:  Menopause       Date:  2013-01       Impact factor: 2.953

  2 in total

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