Literature DB >> 1360672

CD8 T cells can protect against an intracellular bacterium in an interferon gamma-independent fashion.

J T Harty1, R D Schreiber, M J Bevan.   

Abstract

Specific T-cell immunity to Listeria monocytogenes is thought to occur through the action of lymphokines which activate phagocytes to ingest and kill microorganisms. Interferon gamma (IFN-gamma) has been shown to be an effective mediator of this type of macrophage activation in vivo and in vitro. The monoclonal antibody H22.1 efficiently neutralizes endogenous IFN-gamma, exacerbates disease in a mouse model of L. monocytogenes infection, and inhibits the in vivo protective activity of a Listeria antigen-specific CD4 T-cell line. In contrast, in vivo protection by Listeria-immune CD8 T cells is not inhibited by the neutralizing anti-IFN-gamma monoclonal antibody. These results suggest that CD8 T cells can protect against an intracellular pathogen in an IFN-gamma-independent manner.

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Year:  1992        PMID： 1360672      PMCID： PMC50603          DOI： 10.1073/pnas.89.23.11612

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  42 in total

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Journal:  Infect Immun       Date:  1988-08       Impact factor: 3.441

2.  Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection.

Authors:  J Nikolić-Zugić; M J Bevan
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

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Journal:  Transplantation       Date:  1982-09       Impact factor: 4.939

4.  Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

Authors:  N A Buchmeier; R D Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

5.  Interferon-gamma: the major mediator of resistance against Toxoplasma gondii.

Authors:  Y Suzuki; M A Orellana; R D Schreiber; J S Remington
Journal:  Science       Date:  1988-04-22       Impact factor: 47.728

6.  Specific Lyt 123 cells are involved in protection against Listeria monocytogenes and in delayed-type hypersensitivity to listerial antigens.

Authors:  S H Kaufmann; M M Simon; H Hahn
Journal:  J Exp Med       Date:  1979-10-01       Impact factor: 14.307

7.  The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

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Journal:  J Exp Med       Date:  1984-08-01       Impact factor: 14.307

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Authors:  F C Lane; E R Unanue
Journal:  J Exp Med       Date:  1972-05-01       Impact factor: 14.307

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Authors:  C F Nathan; H W Murray; M E Wiebe; B Y Rubin
Journal:  J Exp Med       Date:  1983-09-01       Impact factor: 14.307

10.  Cellular resistance to infection.

Authors:  G B MACKANESS
Journal:  J Exp Med       Date:  1962-09-01       Impact factor: 14.307
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  48 in total

Review 1.  From hot dogs to CD8+ T cells: Listeria monocytogenes.

Authors:  E J Wing; S H Gregory
Journal:  Trans Am Clin Climatol Assoc       Date:  2000

2.  Stress-induced ClpP serine protease of Listeria monocytogenes is essential for induction of listeriolysin O-dependent protective immunity.

Authors:  O Gaillot; S Bregenholt; F Jaubert; J P Di Santo; P Berche
Journal:  Infect Immun       Date:  2001-08       Impact factor: 3.441

Review 3.  Listeria pathogenesis and molecular virulence determinants.

Authors:  J A Vázquez-Boland; M Kuhn; P Berche; T Chakraborty; G Domínguez-Bernal; W Goebel; B González-Zorn; J Wehland; J Kreft
Journal:  Clin Microbiol Rev       Date:  2001-07       Impact factor: 26.132

4.  Elimination of resident macrophages from the livers and spleens of immune mice impairs acquired resistance against a secondary Listeria monocytogenes infection.

Authors:  J N Samsom; A Annema; P H Groeneveld; N van Rooijen; J A Langermans; R van Furth
Journal:  Infect Immun       Date:  1997-03       Impact factor: 3.441

5.  Nutrition, immunity and infection: from basic knowledge of dietary manipulation of immune responses to practical application of ameliorating suffering and improving survival.

Authors:  R K Chandra
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-10       Impact factor: 11.205

6.  Fas (CD95)-dependent cell-mediated immunity to Listeria monocytogenes.

Authors:  E R Jensen; A A Glass; W R Clark; E J Wing; J F Miller; S H Gregory
Journal:  Infect Immun       Date:  1998-09       Impact factor: 3.441

7.  The aryl hydrocarbon receptor is required for optimal resistance to Listeria monocytogenes infection in mice.

Authors:  Lewis Zhichang Shi; Nancy G Faith; Yumi Nakayama; Makulasiddappa Suresh; Howard Steinberg; Charles J Czuprynski
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

8.  The role of gammadelta T cells in induction of bacterial antigen-specific protective CD8+ cytotoxic T cells in immune response against the intracellular bacteria Listeria monocytogenes.

Authors:  A Nomura; G Matsuzaki; H Takada; K Hiromatsu; S Nabeshima; T Nakamura; K Kishihara; K Nomoto
Journal:  Immunology       Date:  1998-10       Impact factor: 7.397

9.  PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.

Authors:  Javier O Valenzuela; Cristina Iclozan; Mohammad S Hossain; Martin Prlic; Emily Hopewell; Crystina C Bronk; Junmei Wang; Esteban Celis; Robert W Engelman; Bruce R Blazar; Michael J Bevan; Edmund K Waller; Xue-Zhong Yu; Amer A Beg
Journal:  J Clin Invest       Date:  2009-11-09       Impact factor: 14.808

10.  A novel IL-17-dependent mechanism of cross protection: respiratory infection with mycoplasma protects against a secondary listeria infection.

Authors:  Amy N Sieve; Karen D Meeks; Sheetal Bodhankar; Suheung Lee; Jay K Kolls; Jerry W Simecka; Rance E Berg
Journal:  Eur J Immunol       Date:  2009-02       Impact factor: 5.532
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