A conservative, low-cost superovulation regimen.

The protocol reported decreases the cost and inconvenience of inducing the growth of multiple ovulatory follicles in selected infertility patients. Safety was maintained by treating patients with relatively small amounts of exogenous gonadotropins and using patient response to slowly increase gonadotropin stimulation in subsequent cycles. The pregnancy rate was 26% per cycle. For couples with male factor infertility, it was 20% per cycle. This regimen may be especially suitable for the practitioner with only a few patients requiring this therapy who may not have the capacity to obtain daily estradiol levels.