Literature DB >> 13602793

Tranquilizing and antiserotonin activity of nicotinamide.

D W WOOLLEY.   

Abstract

Nicotinamide in large amounts antagonized the action of serotonin on smooth muscles in vitro and in vivo. It also tranquilized animals. The antagonism differed in some respects from that of an antimetabolite of serotonin.

Entities:  

Keywords:  MUSCLES/effect of drugs on; NICOTINIC ACID/related compounds; SEROTONIN/antagonists; TRANQUILIZING AGENTS

Mesh:

Substances:

Year:  1958        PMID: 13602793     DOI: 10.1126/science.128.3334.1277

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  EXPLORATION OF THE INTERRELATIONSHIP OF SEROTONIN WITH THE EPINEPHRINES AND HISTAMINE.

Authors:  D W Woolley
Journal:  Proc Natl Acad Sci U S A       Date:  1960-07       Impact factor: 11.205

2.  The sedative effects of nicotinamide on gerbil wheel-running activity.

Authors:  J M Beaton
Journal:  Experientia       Date:  1976-08-15
  2 in total

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