Literature DB >> 1359832

Toremifene resistance in a rat mammary tumour model.

J A Kellen1, E Georges, V Ling, M Dubsky.   

Abstract

The effect of Toremifene on cell growth in vitro was tested on the R3230AC rat mammary adenocarcinoma as model. Toremifene differed from Tamoxifen in that it did not induce resistance; some cross-resistance was observed in Tamoxifen tolerant tumour cell lines. Toremifene does not influence P-glycoprotein expression in this model and at the levels studied.

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Year:  1992        PMID: 1359832

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  1 in total

Review 1.  Toremifene in postmenopausal breast cancer. Efficacy, safety and cost.

Authors:  J U Mäenpää; S L Ala-Fossi
Journal:  Drugs Aging       Date:  1997-10       Impact factor: 3.923

  1 in total

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