| Literature DB >> 1359557 |
D J Balding1, R A Nichols, D M Hunt.
Abstract
The effects of gene conversion can be detected in the DNA sequences of multigene families. We develop a permutation test of the significance of patterns of sequence mismatches, and apply it to the sequences of the red- and green-sensitive visual pigment genes of human and the diana monkey. Whereas conventional tests of the rate of sequence divergence are equivocal, the permutation test convincingly excludes divergence in the absence of gene conversion (p = 10(-6)).Entities:
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Year: 1992 PMID： 1359557 DOI： 10.1098/rspb.1992.0114
Source DB: PubMed Journal: Proc Biol Sci ISSN： 0962-8452 Impact factor: 5.349