Literature DB >> 13592275

Effect of reserpine pretreatment on stimulation of the accelerans nerve of the dog.

U TRENDELENBURG, J S GRAVENSTEIN.   

Abstract

Pretreatment with two doses of reserpine (each 0.1 mg/kg, intraperitoneally) sensitizes the heart to the positive chronotropic action of norepinephrine and reduces the response to stimulation of the accelerans nerve. Ganglionic transmission remains unaffected. The results indicate that the presence of certain stores of peripheral sympathetic transmitter is essential for the production of tachycardia by stimulation of the accelerans nerve.

Entities:  

Keywords:  DEFECTS, CONGENITAL/effect of drugs on; RESERPINE/effects

Mesh：

Substances：

Year:  1958        PMID： 13592275     DOI： 10.1126/science.128.3329.901-a

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  THE INFLUENCE OF RESERPINE PRETREATMENT UPON THE HEMODYNAMICS OF DOGS DURING HEMORRHAGIC HYPOTENSION.

Authors:  E SEIFEN; W FLACKE; M H ALPER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1964-04-21

2.  THE EFFECT OF RESERPINE PRETREATMENT ON THE HYPOTENSIVE ACTION OF THIOPENTAL.

Authors:  J M STUMP; W W FLEMING
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1964-05-11

3.  THE INFLUENCE OF ACUTE SYMPATHETIC DENERVATION, RESERPINE AND CHOLINE XYLYL ETHER ON VAGAL ESCAPE.

Authors:  H A CAMPOS; A H FRIEDMAN
Journal:  J Physiol       Date:  1963-11       Impact factor: 5.182

4.  CARDIAC NOREPHINEPHRINE STORES IN EXPERIMENTAL HEART FAILURE IN THE DOG.

Authors:  C A CHIDSEY; G A KAISER; E H SONNENBLICK; J F SPANN; E BRAUNWALD
Journal:  J Clin Invest       Date:  1964-12       Impact factor: 14.808

5.  The influence of reserpine upon the changes in femoral blood flow produced by stimulation of the lumbar sympathetic chain.

Authors:  D R WAUD
Journal:  Experientia       Date:  1961-05-15

6.  Preganglionic sympathetic activity in normal and in reserpine-treated cats.

Authors:  A IGGO; M VOGT
Journal:  J Physiol       Date:  1960-01       Impact factor: 5.182

7.  Supersensitivity of salivary glands following treatment with bretylium or guanethidine.

Authors:  N EMMELIN; J ENGSTROM
Journal:  Br J Pharmacol Chemother       Date:  1961-06

8.  Depletion of heart norepinephrine in experimental acute myocarditis caused by Trypanosoma cruzi.

Authors:  A B Machado; C R Machado; C B Gomes
Journal:  Experientia       Date:  1975-10-15

9.  The effect of stimulation of sympathetic nerves in the cat treated with reserpine, alpha-methyldopa and alpha-methylmetatyrosine.

Authors:  W Haefely; A Hürlimann; H Thoenen
Journal:  Br J Pharmacol Chemother       Date:  1966-01

10.  Selective reserpine-induced supersensitivity of the positive inotropic and chronotropic responses to isoprenaline and salbutamol in guinea-pig isolated atria.

Authors:  K J Broadley; P Lumley
Journal:  Br J Pharmacol       Date:  1977-01       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.