Literature DB >> 1359095

Effect of compressional forces on piroxicam polymorphs.

G A Ghan1, J K Lalla.   

Abstract

The effect of compressional force on the polymorphic transition in piroxicam has been examined, using pure polymorph, by differential scanning calorimetry, powder X-ray diffractometry and by determination of dissolution rates from tablets of the individual polymorphs. The needle shaped polymorph was found to undergo transition to the cubic polymorph during compression.

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Year:  1992        PMID: 1359095     DOI: 10.1111/j.2042-7158.1992.tb05494.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  2 in total

1.  Use of drifts and PLS for the determination of polymorphs of piroxicam alone and in combination with pharmaceutical excipients: a technical note.

Authors:  Vimon Tantishaiyakul; Pattakarn Permkam; Krit Suknuntha
Journal:  AAPS PharmSciTech       Date:  2008-01-15       Impact factor: 3.246

2.  Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction.

Authors:  Vishal Koradia; Mikko Tenho; Heidi Lopez de Diego; Michiel Ringkjøbing-Elema; Jørn Møller-Sonnergaard; Jarno Salonen; Vesa-Pekka Lehto; Jukka Rantanen
Journal:  Pharm Res       Date:  2011-07-09       Impact factor: 4.200

  2 in total

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