Identical photosensitizing activities of a sulfonated aluminium phthalocyanine on human erythroleukemia cell lines susceptible or resistant to the cytotoxic activity of doxorubicin.

In this paper we report that a human erythroleukemia cell line made 100 times more resistant than the parental line to the cytostatic activity of doxorubicin and spontaneously 500-1000 times more resistant to the cytostatic activity of an unrelated drug, namely taxol, exhibits on the other hand unchanged susceptibility to the photosensitizing activity of a sulfonated phthalocyanine.