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Literature DB >> 1358608

Structures and functions of the sugar chains of glycoproteins.

Abstract

Most proteins within living organisms contain sugar chains. Recent advancements in cell biology have revealed that many of these sugar chains play important roles as signals for cell-surface recognition phenomena in multi-cellular organisms. In order to elucidate the biological information included in the sugar chains and link them with biology, a novel scientific field called 'glycobiology' has been established. This review will give an outline of the analytical techniques for the structural study of the sugar chains of glycoproteins, the structural characteristics of the sugar chains and the biosynthetic mechanism to produce such characteristics. Based on this knowledge, functional aspects of the sugar chains of glycohormones and of those in the immune system will be described to help others understand this new scientific field.

Entities: Chemical

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Year: 1992 PMID： 1358608 DOI： 10.1111/j.1432-1033.1992.tb17313.x

Source DB: PubMed Journal: Eur J Biochem ISSN： 0014-2956

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Cited

59 in total

1. Identification and localisation of glycoconjugates in the olfactory mucosa of the armadillo Chaetophractus villosus.

Authors: C C Ferrari; P D Carmanchahi; H J Aldana Marcos; M T Mugnaini; J M Affanni; D A Paz
Journal: J Anat Date: 1999-04 Impact factor: 2.610

2. Isolation and characterisation of the cDNA encoding a glycosylated accessory protein of pea chloroplast DNA polymerase.

Authors: A Gaikwad; K K Tewari; D Kumar; W Chen; S K Mukherjee
Journal: Nucleic Acids Res Date: 1999-08-01 Impact factor: 16.971

3. Effect of pH, temperature and alcohols on the stability of glycosylated and deglycosylated stem bromelain.

Authors: Rizwan Hasan Khan; Sheeba Rasheedi; Soghra Khatun Haq
Journal: J Biosci Date: 2003-12 Impact factor: 1.826

4. Mitochondrial glycosidic residues contribute to the interaction between ruthenium amine complexes and the calcium uniporter.

Authors: Francisco Correa; Cecilia Zazueta
Journal: Mol Cell Biochem Date: 2005-04 Impact factor: 3.396

5. Profiling terminal N-acetyllactosamines of glycans on mammalian cells by an immuno-enzymatic assay.

Authors: Haruko Ogawa; Uri Galili
Journal: Glycoconj J Date: 2006-11-18 Impact factor: 2.916

6. Congenital disorders of glycosylation type I: a rare but new cause of hyperechoic kidneys in infants and children due to early microcystic changes.

Authors: Lucie Hertz-Pannier; Michele Déchaux; Martine Sinico; Sophie Emond; Valerie Cormier-Daire; Jean-Marie Saudubray; Francis Brunelle; Patrick Niaudet; Nathalie Seta; Pascale de Lonlay
Journal: Pediatr Radiol Date: 2005-11-22

Structures and functions of the sugar chains of glycoproteins.

1. Identification and localisation of glycoconjugates in the olfactory mucosa of the armadillo Chaetophractus villosus.

2. Isolation and characterisation of the cDNA encoding a glycosylated accessory protein of pea chloroplast DNA polymerase.

3. Effect of pH, temperature and alcohols on the stability of glycosylated and deglycosylated stem bromelain.

4. Mitochondrial glycosidic residues contribute to the interaction between ruthenium amine complexes and the calcium uniporter.

5. Profiling terminal N-acetyllactosamines of glycans on mammalian cells by an immuno-enzymatic assay.

6. Congenital disorders of glycosylation type I: a rare but new cause of hyperechoic kidneys in infants and children due to early microcystic changes.

7. Using cell engineering and omic tools for the improvement of cell culture processes.

8. Related effects of cell adaptation to serum-free conditions on murine EPO production and glycosylation by CHO cells.

9. Cell type-dependent alterations of binding of synthetic blood group antigen-related oligosaccharides in lung cancer.

10. Glycoconjugate expression of chondrocytes and perichondrium during hyaline cartilage development in the rat.