Literature DB >> 1358489

Nucleotide sequence and PCR-amplification of a polymorphic MboI site in human DNA marker D4S95 linked to the Huntington disease locus.

A Nørremølle1, S A Sørensen, P Arctander.   

Abstract

The nucleotide sequence of the probe BS674E-D defining the genetic locus D4S95 was assessed, and used for designing PCR-primers amplifying a 175 bp fragment containing a polymorphic MboI site. With the described conditions it is now possible to use PCR followed by digestion for rapid determination of genotype in this marker system.

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Year:  1992        PMID: 1358489     DOI: 10.1111/j.1399-0004.1992.tb03240.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN: 0009-9163            Impact factor:   4.438


  1 in total

1.  Amplification and detection of the VNTR locus D4S95 in a Japanese population.

Authors:  K Honda; M Nakatome; M N Islam; H Bai; Y Ogura; H Kuroki; M Yamazaki; M Terada; C Wakasugi
Journal:  Int J Legal Med       Date:  1995       Impact factor: 2.686

  1 in total

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