| Literature DB >> 135810 |
Abstract
Purified human lymphocyte interferon (PIF) was added to mixed lymphocyte cultures; DNA synthesis was measured and killer-cell generation was determined. At certain concentrations, PIF ingibited proliferation, but at the same time increased the killer efficiency of the resultant culture cells. It is suggested that lymphokines, apart from their normal mediator function, may play a role as regulators of the generating immune response.Entities:
Mesh：
Substances：
Year: 1976 PMID： 135810
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422