Literature DB >> 1357964

DNA polymorphism of alkaline phosphatase isozyme genes: linkage disequilibria between placental and germ-cell alkaline phosphatase alleles.

G Beckman1, L Beckman, C Sikström, J L Millán.   

Abstract

The use of human placental alkaline phosphatase (PLAP) cDNA as a probe allows the detection and identification of restriction DNA fragments derived from three homologous genes, i.e., intestinal alkaline phosphatase (AP), germ-cell AP (GCAP), and PLAP. In previous RFLP studies we have reported linkage disequilibria between an RsaI and two PstI (a and b) polymorphic restriction sites and electrophoretic types of PLAP. In this report we present evidence that, in spite of the strong correlation with PLAP types, PstI(b) is an RFLP of GCAP. The data indicate close linkage between the PLAP and GCAP loci.

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Year:  1992        PMID： 1357964      PMCID： PMC1682846     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  17 in total

1.  A new PstI restriction fragment length polymorphism (RFLP) of placental alkaline phosphatase. RFLP haplotypes and correlation with electrophoretic types.

Authors:  G Beckman; L Beckman; A Kivelä; J L Millán; C Sikström
Journal:  Hum Hered       Date:  1991       Impact factor: 0.444

2.  Pst I restriction fragment length polymorphism of human placental alkaline phosphatase gene: Mendelian segregation and localization of mutation site in the gene.

Authors:  L Tsavaler; R C Penhallow; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

3.  Genetic variants of placental alkaline phosphatase as detected by a monoclonal antibody.

Authors:  J L Millán; G Beckman; A Jeppsson; T Stigbrand
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

4.  Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution.

Authors:  B J Knoll; K N Rothblum; M Longley
Journal:  J Biol Chem       Date:  1988-08-25       Impact factor: 5.157

5.  Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA.

Authors:  W Kam; E Clauser; Y S Kim; Y W Kan; W J Rutter
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

6.  Sequence and characterization of the human intestinal alkaline phosphatase gene.

Authors:  P S Henthorn; M Raducha; T Kadesch; M J Weiss; H Harris
Journal:  J Biol Chem       Date:  1988-08-25       Impact factor: 5.157

7.  Pst I restriction fragment length polymorphism of the human placental alkaline phosphatase gene in normal placentae and tumors.

Authors:  L Tsavaler; R C Penhallow; W Kam; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

8.  Molecular cloning and sequence analysis of human placental alkaline phosphatase.

Authors:  J L Millán
Journal:  J Biol Chem       Date:  1986-03-05       Impact factor: 5.157

9.  Seminoma-derived Nagao isozyme is encoded by a germ-cell alkaline phosphatase gene.

Authors:  J L Millán; T Manes
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

10.  RFLP of the human placental alkaline phosphatase gene (PLAP).

Authors:  D Martin; N K Spurr; J Trowsdale
Journal:  Nucleic Acids Res       Date:  1987-11-11       Impact factor: 16.971
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  1 in total

1.  Postnatal development- and age-related changes in DNA-methylation patterns in the human genome.

Authors:  Paraskevi Salpea; Valya R Russanova; Tazuko H Hirai; Thomae G Sourlingas; Kalliope E Sekeri-Pataryas; Roberto Romero; Jonathan Epstein; Bruce H Howard
Journal:  Nucleic Acids Res       Date:  2012-04-11       Impact factor: 16.971
  1 in total

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