Literature DB >> 1357922

Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties.

R Bullock1, Y Kuroda, G M Teasdale, J McCulloch.   

Abstract

Excitotoxic mechanisms due to overactivity of the amino acid neurotransmitters glutamate and aspartate maybe responsible for brain damage after injury. In this review we examine ischaemia and shear injury, which are relevant to human head injury. The opportunities for treatment using glutamate antagonist drugs are discussed.

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Year:  1992        PMID： 1357922     DOI： 10.1007/978-3-7091-9233-7_15

Source DB:  PubMed          Journal:  Acta Neurochir Suppl (Wien)


  5 in total

Review 1.  Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurological Outcomes.

Authors:  Helen M Bramlett; W Dalton Dietrich
Journal:  J Neurotrauma       Date:  2014-12-19       Impact factor: 5.269

Review 2.  Critical appraisal of neuroprotection trials in head injury: what have we learned?

Authors:  Christos M Tolias; M Ross Bullock
Journal:  NeuroRx       Date:  2004-01

3.  Systematic review of the pharmacological agents that have been tested against spreading depolarizations.

Authors:  Anna Klass; Renan Sánchez-Porras; Edgar Santos
Journal:  J Cereb Blood Flow Metab       Date:  2018-04-20       Impact factor: 6.200

4.  Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide.

Authors:  Seok Joon Won; Bo Young Choi; Byung Hoon Yoo; Min Sohn; Weihai Ying; Raymond A Swanson; Sang Won Suh
Journal:  J Neurotrauma       Date:  2012-04-17       Impact factor: 5.269

5.  Neuroprotective effects of tetracyclines on blunt head trauma: An experimental study on rats.

Authors:  Ozhan Merzuk Uckun; Fatih Alagoz; Mehmet Secer; Oguz Karakoyun; Ayhan Ocakcioglu; Ali Erdem Yildirim; Fevzi Yımaz; Mert Sahinoglu; Denizhan Divanlioglu; Ali Dalgic; Ergun Daglioglu; Ahmet Deniz Belen
Journal:  J Neurosci Rural Pract       Date:  2015-01
  5 in total

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