Literature DB >> 1357886

Can alopecia areata be triggered by emotional stress? An uncontrolled evaluation of 178 patients with extensive hair loss.

P van der Steen1, J Boezeman, P Duller, R Happle.   

Abstract

One hundred and seventy-eight patients with severe alopecia areata were asked at interview whether they attributed their first attack of hair loss to an emotional trauma. Twelve patients (6.7%) reported a severely disturbing event during the 6 months preceding the first symptoms of their disease. No patient reported that episodes of hair loss coincided with stressful life events. Emotional triggers were not especially correlated with any particular type of alopecia areata. The present study does not therefore provide evidence of a significant role of emotional stress in the pathogenesis of alopecia areata.

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Year:  1992        PMID: 1357886     DOI: 102340/0001555572279280

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   4.437


  10 in total

Review 1.  [Alopecia areata. Clinical aspects, pathogenesis and rational therapy of a T-cell-induced autoimmune disease].

Authors:  P Freyschmidt-Paul; R Happle; R Hoffmann
Journal:  Hautarzt       Date:  2003-08       Impact factor: 0.751

Review 2.  Stress-related skin disorders.

Authors:  Alex Alexopoulos; George P Chrousos
Journal:  Rev Endocr Metab Disord       Date:  2016-09       Impact factor: 6.514

3.  Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways.

Authors:  Petra Clara Arck; Bori Handjiski; Eva Milena J Peters; Anita S Peter; Evelin Hagen; Axel Fischer; Burghard F Klapp; Ralf Paus
Journal:  Am J Pathol       Date:  2003-03       Impact factor: 4.307

4.  Serum cytokine levels and anxiety and depression rates in patients with alopecia areata.

Authors:  Arzu Ataseven; Yunus Saral; Ahmet Godekmerdan
Journal:  Eurasian J Med       Date:  2011-08

5.  Surgical methods for full-thickness skin grafts to induce alopecia areata in C3H/HeJ mice.

Authors:  Kathleen A Silva; John P Sundberg
Journal:  Comp Med       Date:  2013-10       Impact factor: 0.982

Review 6.  Key role of CRF in the skin stress response system.

Authors:  Andrzej T Slominski; Michal A Zmijewski; Blazej Zbytek; Desmond J Tobin; Theoharis C Theoharides; Jean Rivier
Journal:  Endocr Rev       Date:  2013-08-12       Impact factor: 19.871

7.  Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model.

Authors:  Xingqi Zhang; Mei Yu; Wayne Yu; Joanne Weinberg; Jerry Shapiro; Kevin J McElwee
Journal:  J Invest Dermatol       Date:  2008-11-20       Impact factor: 8.551

8.  Psychosocial and psychiatric comorbidities and health-related quality of life in alopecia areata: A systematic review.

Authors:  Atrin Toussi; Virginia R Barton; Stephanie T Le; Oma N Agbai; Maija Kiuru
Journal:  J Am Acad Dermatol       Date:  2020-06-17       Impact factor: 15.487

9.  Concepts of patients with alopecia areata about their disease.

Authors:  Alireza Firooz; Mehdi Rashighi Firoozabadi; Behnaz Ghazisaidi; Yahya Dowlati
Journal:  BMC Dermatol       Date:  2005-01-12

10.  Impact of Psychosocial Profile on Alopecia Areata in Pediatric Patients: A Case Control Study from A Tertiary Care Hospital in Eastern Uttar Pradesh.

Authors:  Neerja Saraswat; Pooja Shankar; Ajay Chopra; Sushil Kumar; Debdeep Mitra; Reetu Agarwal
Journal:  Indian J Dermatol       Date:  2020 May-Jun       Impact factor: 1.494

  10 in total

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