Literature DB >> 1357246

Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn.

J P Kinsella1, S R Neish, E Shaffer, S H Abman.   

Abstract

We studied the effects of inhaled nitric oxide (NO) in 9 newborn infants with severe persistent pulmonary hypertension (PPHN) who were candidates for extracorporeal membrane oxygenation treatment. With low doses of NO (10-20 ppm) all showed rapid improvement in oxygenation without reduction of systemic blood pressure. In 6 infants treated with inhaled NO for 24 h, clinical improvement was sustained at 6 ppm.

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Year:  1992        PMID： 1357246     DOI： 10.1016/0140-6736(92)92687-b

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  90 in total

Review 1.  Response to inhaled nitric oxide in premature and term neonates.

Authors:  T Hoehn; M F Krause
Journal:  Drugs       Date:  2001       Impact factor: 9.546

Review 2.  Inhaled nitric oxide treatment for preterm infants with hypoxic respiratory failure.

Authors:  R L Smyth
Journal:  Thorax       Date:  2000-08       Impact factor: 9.139

3.  Cerebral blood flow during treatment for pulmonary hypertension.

Authors:  S Kusuda; N Shishida; N Miyagi; M Hirabayashi; T J Kim
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1999-01       Impact factor: 5.747

4.  Endothelial nitric oxide synthase in hypoxic newborn porcine pulmonary vessels.

Authors:  A A Hislop; D R Springall; H Oliveira; J S Pollock; J M Polak; S G Haworth
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1997-07       Impact factor: 5.747

Review 5.  Congenital diaphragmatic hernia.

Authors:  M Arora; M Bajpai; T R Soni; T R Prasad
Journal:  Indian J Pediatr       Date:  2000-09       Impact factor: 1.967

6.  Inhaled nitric oxide delivery and monitoring.

Authors:  F J Montgomery; A D Berssenbrugge
Journal:  J Clin Monit Comput       Date:  1999-07       Impact factor: 2.502

Review 7.  Neonatal non-invasive respiratory support: physiological implications.

Authors:  Thomas H Shaffer; Deepthi Alapati; Jay S Greenspan; Marla R Wolfson
Journal:  Pediatr Pulmonol       Date:  2012-07-06

8.  Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome.

Authors:  H Gerlach; D Pappert; K Lewandowski; R Rossaint; K J Falke
Journal:  Intensive Care Med       Date:  1993       Impact factor: 17.440

9.  Alternatives to ECMO.

Authors:  S M Donn
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1994-03       Impact factor: 5.747

10.  Methaemoglobin production in normal adults inhaling low concentrations of nitric oxide.

Authors:  J D Young; O Dyar; L Xiong; S Howell
Journal:  Intensive Care Med       Date:  1994-11       Impact factor: 17.440
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