OBJECTIVE: To assess the value of ultrasonography together with C reactive protein concentration in predicting which patients with acute cholecystitis require immediate operation. DESIGN: Prospective study. SETTING: Oulu University Hospital, Finland. SUBJECTS: 129 consecutive patients admitted with suspected acute cholecystitis 1988-89. MAIN OUTCOME MEASURES: Correlation of ultrasonographic findings and C reactive protein concentrations with histological findings. RESULTS: Ultrasonography correctly classified 86 of 108 patients with acute cholecystitis (79%). When the findings were combined with those of increased concentrations of C reactive protein the accuracy rose to 105 of 108 (97%). Large increases in C reactive protein concentrations were associated with both infected bile and gangrene of the gall bladder. CONCLUSIONS: The combination of ultrasonography and measurement of C reactive protein concentration is recommended in the routine investigation of all patients with suspected acute cholecystitis. Serum C reactive protein concentrations should be monitored regularly to select those patients who require emergency operation.
OBJECTIVE: To assess the value of ultrasonography together with C reactive protein concentration in predicting which patients with acute cholecystitis require immediate operation. DESIGN: Prospective study. SETTING: Oulu University Hospital, Finland. SUBJECTS: 129 consecutive patients admitted with suspected acute cholecystitis 1988-89. MAIN OUTCOME MEASURES: Correlation of ultrasonographic findings and C reactive protein concentrations with histological findings. RESULTS: Ultrasonography correctly classified 86 of 108 patients with acute cholecystitis (79%). When the findings were combined with those of increased concentrations of C reactive protein the accuracy rose to 105 of 108 (97%). Large increases in C reactive protein concentrations were associated with both infected bile and gangrene of the gall bladder. CONCLUSIONS: The combination of ultrasonography and measurement of C reactive protein concentration is recommended in the routine investigation of all patients with suspected acute cholecystitis. Serum C reactive protein concentrations should be monitored regularly to select those patients who require emergency operation.
Authors: Masahiko Hirota; Tadahiro Takada; Yoshifumi Kawarada; Yuji Nimura; Fumihiko Miura; Koichi Hirata; Toshihiko Mayumi; Masahiro Yoshida; Steven Strasberg; Henry Pitt; Thomas R Gadacz; Eduardo de Santibanes; Dirk J Gouma; Joseph S Solomkin; Jacques Belghiti; Horst Neuhaus; Markus W Büchler; Sheung-Tat Fan; Chen-Guo Ker; Robert T Padbury; Kui-Hin Liau; Serafin C Hilvano; Giulio Belli; John A Windsor; Christos Dervenis Journal: J Hepatobiliary Pancreat Surg Date: 2007-01-30
Authors: L Ansaloni; M Pisano; F Coccolini; A B Peitzmann; A Fingerhut; F Catena; F Agresta; A Allegri; I Bailey; Z J Balogh; C Bendinelli; W Biffl; L Bonavina; G Borzellino; F Brunetti; C C Burlew; G Camapanelli; F C Campanile; M Ceresoli; O Chiara; I Civil; R Coimbra; M De Moya; S Di Saverio; G P Fraga; S Gupta; J Kashuk; M D Kelly; V Koka; H Jeekel; R Latifi; A Leppaniemi; R V Maier; I Marzi; F Moore; D Piazzalunga; B Sakakushev; M Sartelli; T Scalea; P F Stahel; K Taviloglu; G Tugnoli; S Uraneus; G C Velmahos; I Wani; D G Weber; P Viale; M Sugrue; R Ivatury; Y Kluger; K S Gurusamy; E E Moore Journal: World J Emerg Surg Date: 2016-06-14 Impact factor: 5.469