Literature DB >> 1355940

[The mechanism of the intranasal action of dermorphin in representatives of 2 classes of vertebrates].

L S Chernova, A A Kamenskiĭ, G A Maliukina, E Iu Baturina, V I Deĭgin, E P Iarova.   

Abstract

It has been shown that endogenous opioid dermorphin induces effective analgesia after intranasal injection to fish (0.02-0.20 mg/kg) and rats (0.005 mg/kg). Maintenance of dermorphin analgesia after olfactory and trigeminal denervation indicates that the analgetic effect is not realized via the olfactory receptors or free terminals of the trigeminal nerve.

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Year:  1992        PMID: 1355940

Source DB:  PubMed          Journal:  Zh Evol Biokhim Fiziol        ISSN: 0044-4529


  2 in total

1.  Opioid modulation of pain threshold in fish.

Authors:  L S Chervova; D N Lapshin
Journal:  Dokl Biol Sci       Date:  2000 Nov-Dec

Review 2.  The evolution of vertebrate opioid receptors.

Authors:  Craig W Stevens
Journal:  Front Biosci (Landmark Ed)       Date:  2009-01-01
  2 in total

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