Literature DB >> 13537141

Metabolism of drugs. XVI. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 6. Studies on the reduction of 3-keto-MHB (5-(3-oxo-1-cyclohexenyl)-3,5-dimethylbarbituric acid) and on pharmacological activity of the biotransformation products of methylhexabital from the urine of rabbits.

H YOSHIMURA.   

Abstract

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Keywords:  BARBITURATES/metabolism

Mesh：

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Year:  1958        PMID： 13537141     DOI： 10.1248/cpb.6.13

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


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  2 in total

1.  Hexobarbital-binding, hydroxylation and hexobarbital-dependent hydrogen peroxide production in hepatic microsomes of guinea pig, rat and rabbit.

Authors:  G Heinemeyer; S Nigam; A G Hildebrandt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-11       Impact factor: 3.000

2.  Disposition of allylic oxidation pathway metabolites of racemic hexobarbital in the rat.

Authors:  M Van der Graaff; N P Vermeulen; M H Vinks; D D Breimer
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1986 Apr-Jun       Impact factor: 2.441
  2 in total

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