Literature DB >> 13535596

Studies on the biosynthesis of cholesterol. 5. Biosynthesis of squalene from DL-3-hydroxy-3-methyl [2-14C] pentano-5-lactone.

J W CORNFORTH, R H CORNFORTH, G POPJAK, I Y GORE.   

Abstract

Entities:  

Keywords:  CHOLESTEROL/metabolism; PYRANS/metabolism; SQUALENE/metabolism

Mesh:

Substances:

Year:  1958        PMID: 13535596      PMCID: PMC1196527          DOI: 10.1042/bj0690146

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


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  11 in total

1.  The enzymatic cleavage of beta-hydroxy-beta-methylglutaryl coenzyme A to acetoacetate and acetyl coenzyme A.

Authors:  B K BACHHAWAT; W G ROBINSON; M J COON
Journal:  J Biol Chem       Date:  1955-10       Impact factor: 5.157

2.  Enzymatic carboxylation of beta-hydroxyisovaleryl coenzyme A.

Authors:  B K BACHHAWAT; W G ROBINSON; M J COON
Journal:  J Biol Chem       Date:  1956-04       Impact factor: 5.157

3.  The significance of certain carboxylic acids as intermediates in the biosynthesis of cholesterol.

Authors:  L F ADAMSON; D M GREENBERG
Journal:  Biochim Biophys Acta       Date:  1957-03

4.  Discovery of a new acetate-replacing factor.

Authors:  E L CRESSON; K FOLKERS; C H HOFFMAN; G D MACRAE; H R SKEGGS; D E WOLF; L D WRIGHT
Journal:  J Bacteriol       Date:  1956-10       Impact factor: 3.490

5.  Enzymatic synthesis of branched chain acids from amino acids.

Authors:  M J COON
Journal:  Fed Proc       Date:  1955-09

6.  Studies on the biosynthesis of cholesterol. 3. Distribution of 14C in squalene biosynthesized from [Me-14C]acetate.

Authors:  J W CORNFORTH; G POPJAK
Journal:  Biochem J       Date:  1954-11       Impact factor: 3.857

7.  Studies of cholesterol biosynthesis. II. Distribution of acetate carbon in the ring structure.

Authors:  J W CORNFORTH; G D HUNTER; G POPJAK
Journal:  Biochem J       Date:  1953-07       Impact factor: 3.857

8.  Biosynthesis of squalene and cholesterol in vitro from acetate-1-C14.

Authors:  G POPJAK
Journal:  Arch Biochem Biophys       Date:  1954-01       Impact factor: 4.013

9.  The origin of the issoctyl side chain of cholesterol.

Authors:  J WUERSCH; R L HUANG; K BLOCH
Journal:  J Biol Chem       Date:  1952-03       Impact factor: 5.157

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  23 in total

1.  The metabolism of cholesterol.

Authors:  B LEWIS
Journal:  Postgrad Med J       Date:  1959-04       Impact factor: 2.401

2.  The in vitro metabolism of desmosterol with adrenal and liver preparations.

Authors:  D S GOODMAN; J AVIGAN; H WILSON
Journal:  J Clin Invest       Date:  1962-12       Impact factor: 14.808

3.  The metabolism of desmosterol in human subjects during triparanol administration.

Authors:  D S GOODMAN; J AVIGAN; H WILSON
Journal:  J Clin Invest       Date:  1962-05       Impact factor: 14.808

4.  Studies on biosynthesis of cholesterol. 8. The effect of Mg2+ and Mn2+ ions and of adenosine triphosphate on enzymic activity of microsomes in sterol biosynthesis from mevalonic acid.

Authors:  L GOSSELIN; G POPJAK
Journal:  Biochem J       Date:  1959-04       Impact factor: 3.857

5.  Studies on the biosynthesis of cholesterol. 9. Formation of phosphorylated derivatives of mevalonic acid in liver-enzyme preparations.

Authors:  A DE WAARD; G POPJAK
Journal:  Biochem J       Date:  1959-11       Impact factor: 3.857

6.  Influence of the thyroid on the synthesis of cholesterol by liver and skin in vitro.

Authors:  K FLETCHER; N B MYANT
Journal:  J Physiol       Date:  1958-12-04       Impact factor: 5.182

7.  The pathogenesis of the hepatic lesion in calves poisoned experimentally with Senecio jacobaea.

Authors:  L M MARKSON
Journal:  Proc R Soc Med       Date:  1960-04

8.  Studies on the site of the feedback control of cholesterol synthesis.

Authors:  M D SIPERSTEIN; M J GUEST
Journal:  J Clin Invest       Date:  1960-04       Impact factor: 14.808

9.  Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver.

Authors:  H R LEVY; G POPJAK
Journal:  Biochem J       Date:  1960-06       Impact factor: 3.857

10.  Studies on the biosynthesis of cholesterol. 6. Coenzyme requirements of liver enzymes for synthesis of squalene and of sterol from DL-3-hydroxy-3-methyl-[2-14C] pentano-5-lactone.

Authors:  G POPJAK; L GOSSELIN; I Y GORE; R G GOULD
Journal:  Biochem J       Date:  1958-06       Impact factor: 3.857

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