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Literature DB >> 1352712

The complete nucleotide sequence of region 1 of the CFA/I fimbrial operon of human enterotoxigenic Escherichia coli.

B J Jordi¹, G A Willshaw, B A van der Zeijst, W Gaastra.

Abstract

The production of the plasmid-encoded fimbrial antigen CFA/I of enterotoxigenic Escherichia coli requires two DNA regions: CFA/I region 1 and CFA/I region 2. These two regions are separated by about 40 kb on the wildtype plasmid. CFA/I region 1 contains the structural genes, whereas CFA/I region 2 contains a positive regulator. The first two genes (cfaA and cfaB) and the cfaD' sequence of region 1 have already been described. Here the total nucleotide sequence of region 1 is presented. Two new genes in region 1 are described, named cfaC and cfaE. The GC content of the genes in region 1 is 33.6% which is substantially lower than normally found in E. coli genes (50%). The codon usage also differs from the standard codons used in E. coli.

Entities: Gene Species

Mesh：

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Year: 1992 PMID： 1352712 DOI： 10.3109/10425179209020811

Source DB: PubMed Journal: DNA Seq ISSN： 1026-7913

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Cited

19 in total

1. CS5 pilus biosynthesis genes from enterotoxigenic Escherichia coli O115:H40.

Authors: T G Duthy; L H Staendner; P A Manning; M W Heuzenroeder
Journal: J Bacteriol Date: 1999-09 Impact factor: 3.490

2. Evolutionary and functional relationships of colonization factor antigen i and other class 5 adhesive fimbriae of enterotoxigenic Escherichia coli.

Authors: Ravi P Anantha; Annette L McVeigh; Lanfong H Lee; Mary K Agnew; Frederick J Cassels; Daniel A Scott; Thomas S Whittam; Stephen J Savarino
Journal: Infect Immun Date: 2004-12 Impact factor: 3.441

Review 3. Evolution of the chaperone/usher assembly pathway: fimbrial classification goes Greek.

Authors: Sean-Paul Nuccio; Andreas J Bäumler
Journal: Microbiol Mol Biol Rev Date: 2007-12 Impact factor: 11.056

Review 4. Bacterial adhesins: common themes and variations in architecture and assembly.

Authors: G E Soto; S J Hultgren
Journal: J Bacteriol Date: 1999-02 Impact factor: 3.490

5. CooB plays a chaperone-like role for the proteins involved in formation of CS1 pili of enterotoxigenic Escherichia coli.

Authors: K Voegele; H Sakellaris; J R Scott
Journal: Proc Natl Acad Sci U S A Date: 1997-11-25 Impact factor: 11.205

10. Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR.

Authors: S Wu; D W Pascual; J L VanCott; J R McGhee; D R Maneval; M M Levine; D M Hone
Journal: Infect Immun Date: 1995-12 Impact factor: 3.441

The complete nucleotide sequence of region 1 of the CFA/I fimbrial operon of human enterotoxigenic Escherichia coli.

1. CS5 pilus biosynthesis genes from enterotoxigenic Escherichia coli O115:H40.

2. Evolutionary and functional relationships of colonization factor antigen i and other class 5 adhesive fimbriae of enterotoxigenic Escherichia coli.

Review 3. Evolution of the chaperone/usher assembly pathway: fimbrial classification goes Greek.

Review 4. Bacterial adhesins: common themes and variations in architecture and assembly.

5. CooB plays a chaperone-like role for the proteins involved in formation of CS1 pili of enterotoxigenic Escherichia coli.

6. Transcriptional control of genes encoding CS1 pili: negative regulation by a silencer and positive regulation by Rns.

7. Shear-enhanced binding of intestinal colonization factor antigen I of enterotoxigenic Escherichia coli.

Review 8. Pili Assembled by the Chaperone/Usher Pathway in Escherichia coli and Salmonella.

9. Genes for CS2 pili of enterotoxigenic Escherichia coli and their interchangeability with those for CS1 pili.

10. Immune responses to novel Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR.