Literature DB >> 13525579

Immunoreactions involving platelets. II. Theoretical analysis of the model.

T L HILL.   

Abstract

Theoretical equations have been derived, using the methods of statistical mechanics, for associations between platelets, antibody, quinidine, and complement, based on a model of an immunoreaction described in the preceding paper of this series. The two cases considered (i.e. the possibilities that quinidine can attach first to antibody or platelets) lead to the same final equations. The comparison of the theoretical results with experimental results is contained in the preceding paper.

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Keywords:  PURPURA, THROMBOPENIC/immunology; QUINIDINE

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Year:  1958        PMID: 13525579      PMCID: PMC2136853          DOI: 10.1084/jem.107.5.691

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  2 in total

1.  IMMUNOREACTIONS INVOLVING PLATELETS. V. POST-TRANSFUSION PURPURA DUE TO A COMPLEMENT-FIXING ANTIBODY AGAINST A GENETICALLY CONTROLLED PLATELET ANTIGEN. A PROPOSED MECHANISM FOR THROMBOCYTOPENIA AND ITS RELEVANCE IN "AUTOIMMUNITY".

Authors:  N R Shulman; R H Aster; A Leitner; M C Hiller
Journal:  J Clin Invest       Date:  1961-09       Impact factor: 14.808

2.  Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia.

Authors:  D J Christie; R H Aster
Journal:  J Clin Invest       Date:  1982-11       Impact factor: 14.808

  2 in total

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