Literature DB >> 1352482

The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis.

K Kakimoto1, T Nakamura, K Ishii, T Takashi, H Iigou, H Yagita, K Okumura, K Onoue.   

Abstract

In order to study how inflammatory cells including autoimmune lymphocytes interact with each other to develop collagen-induced arthritis (CIA), we injected monoclonal antibodies against mouse LFA-1 and ICAM-1 into DBA/1 mice immunized with type II collagen (CII). Both antibodies suppressed the development of CIA. These antibodies showed no effect on anti-CII antibody response, although they both significantly suppressed DTH response. It was suggested that anti-adhesion molecule antibodies suppress CIA mainly through their effect on cell-mediated immunity, without affecting humoral immunity under the conditions used.

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Year:  1992        PMID： 1352482     DOI： 10.1016/0008-8749(92)90294-y

Source DB:  PubMed          Journal:  Cell Immunol        ISSN： 0008-8749            Impact factor:   4.868


  20 in total

Review 1.  New therapies in development for autoimmune diseases: their rationale for combination treatment.

Authors:  V Strand
Journal:  Springer Semin Immunopathol       Date:  2001

2.  Vascular cell adhesion molecule-1 (VCAM-1) blockade in collagen-induced arthritis reduces joint involvement and alters B cell trafficking.

Authors:  R A Carter; I K Campbell; K L O'Donnel; I P Wicks
Journal:  Clin Exp Immunol       Date:  2002-04       Impact factor: 4.330

3.  Role of intercellular adhesion molecule 1 in pathogenesis of staphylococcal arthritis and in host defense against staphylococcal bacteremia.

Authors:  M Verdrengh; T A Springer; J C Gutierrez-Ramos; A Tarkowski
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

4.  Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion.

Authors:  N Utoguchi; T Nakata; H H Cheng; K Ikeda; H Makimoto; Y Mu; S Nakagawa; M Kobayashi; I Kitagawa; T Mayumi
Journal:  Inflammation       Date:  1997-04       Impact factor: 4.092

5.  Absence of β2 integrins impairs regulatory T cells and exacerbates CD4+ T cell-dependent autoimmune carditis.

Authors:  Stefanie Haasken; Jennifer L Auger; Bryce A Binstadt
Journal:  J Immunol       Date:  2011-07-27       Impact factor: 5.422

Review 6.  Target effector role of vascular endothelium in the inflammatory response: insights from the clinical trial of anti-TNF alpha antibody in rheumatoid arthritis.

Authors:  E Paleolog
Journal:  Mol Pathol       Date:  1997-10

7.  Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis.

Authors:  A R de Fougerolles; A G Sprague; C L Nickerson-Nutter; G Chi-Rosso; P D Rennert; H Gardner; P J Gotwals; R R Lobb; V E Koteliansky
Journal:  J Clin Invest       Date:  2000-03       Impact factor: 14.808

8.  The effects of mesoporphyrin on experimental arthritis in mice.

Authors:  H Nagai; Y Takaoka; H Mori; N Matsuura
Journal:  Inflamm Res       Date:  1996-06       Impact factor: 4.575

9.  Circulating intercellular adhesion molecule 1 as a new activity marker in patients with systemic lupus erythematosus.

Authors:  E Kling; S Bieg; M Boehme; W A Scherbaum
Journal:  Clin Investig       Date:  1993-04

10.  Opioid control of inflammatory pain regulated by intercellular adhesion molecule-1.

Authors:  Halina Machelska; Shaaban A Mousa; Alexander Brack; Julia K Schopohl; Heike L Rittner; Michael Schafer; Christoph Stein
Journal:  J Neurosci       Date:  2002-07-01       Impact factor: 6.167
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