Literature DB >> 13523146

A comparison of antifibrillatory drugs in the heart-lung preparation.

M J RAND, J M WALKER.   

Abstract

Quinidine, amethocaine, Trasentin and atropine have been tested for their ability to stop atrial fibrillation produced in the heart-lung preparation of the dog by stimulating the right atrium in the presence of acetylcholine. The results suggest that atropine acts by specifically antagonizing acetylcholine, but that amethocaine and Trasentin act chiefly by virtue of their quinidine-like properties.

Entities:  

Keywords:  AURICULAR FIBRILLATION/experimental; VESSELS/physiology

Mesh:

Substances:

Year:  1958        PMID: 13523146      PMCID: PMC1481697          DOI: 10.1111/j.1476-5381.1958.tb00201.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  1 in total

1.  The effects of acetylcholine in the heart-lung preparation including the production of auricular fibrillation.

Authors:  J H BURN; E M V WILLIAMS; J M WALKER
Journal:  J Physiol       Date:  1955-05-27       Impact factor: 5.182

  1 in total
  2 in total

1.  Role of ventricular premature beats in initiation and termination of atrial arrhythmias.

Authors:  G Csapó
Journal:  Br Heart J       Date:  1971-01

2.  The mode of action of quinidine on isolated rabbit atria interpreted from intracellular potential records.

Authors:  E M VAUGHAN WILLIAMS
Journal:  Br J Pharmacol Chemother       Date:  1958-09
  2 in total

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