| Literature DB >> 1352264 |
R Goto1, K Muramoto, M Yamazaki, H Kamiya.
Abstract
A D-galactose-specific agglutinin, named sinularian, has been isolated from the soft coral Sinularia sp. by affinity chromatography on acid-treated Sepharose 4B and by gel filtration on HPLC. Sinularian was a glycoprotein containing 11% sugar. It gave a single band corresponding to 78 kDa in SDS-PAGE, irrespective of a treatment with 2-mercaptoethanol. Sinularian agglutinated rabbit erythrocytes and murine leukemia cells but not sheep or human ABO erythrocytes. Its hemagglutinating activity was Ca(++)-independent. Sinularian promoted binding of macrophages to tumor cells.Entities:
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Year: 1992 PMID： 1352264 DOI： 10.1016/0145-305x(92)90047-g
Source DB: PubMed Journal: Dev Comp Immunol ISSN： 0145-305X Impact factor: 3.636