Literature DB >> 1352260

ATP and GTP as alternative energy sources for vinblastine transport by P-170 in KB-V1 plasma membrane vesicles.

I H Lelong1, R Padmanabhan, E Lovelace, I Pastan, M M Gottesman.   

Abstract

Purified plasma membrane vesicles isolated from multidrug-resistant human KB-V1 cells accumulate [3H]vinblastine in an energy-dependent manner. The accumulation of [3H]vinblastine in the presence of ATP is a saturable process. ATP can be replaced by other purine nucleotide triphosphates, of which GTP is the most efficient.

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Year:  1992        PMID： 1352260     DOI： 10.1016/0014-5793(92)80632-q

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

1.  ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter.

Authors:  S Paul; L M Breuninger; K D Tew; H Shen; G D Kruh
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

2.  Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution.

Authors:  Jin Wang; Fang Sun; Da-wei Zhang; Yongming Ma; Fang Xu; Jitendra D Belani; Jonathan C Cohen; Helen H Hobbs; Xiao-Song Xie
Journal:  J Biol Chem       Date:  2006-07-25       Impact factor: 5.157

Review 3.  Molecular analysis of the multidrug transporter.

Authors:  U A Germann
Journal:  Cytotechnology       Date:  1993       Impact factor: 2.058

4.  Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells.

Authors:  F J Sharom; X Yu; J W Chu; C A Doige
Journal:  Biochem J       Date:  1995-06-01       Impact factor: 3.857

Review 5.  The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.

Authors:  John Golin; Suresh V Ambudkar
Journal:  Biochem J       Date:  2015-05-01       Impact factor: 3.857

Review 6.  Altered drug translocation mediated by the MDR protein: direct, indirect, or both?

Authors:  P D Roepe; L Y Wei; M M Hoffman; F Fritz
Journal:  J Bioenerg Biomembr       Date:  1996-12       Impact factor: 2.945

7.  Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells.

Authors:  Tomoko Konishi; Hideo Satsu; Yasuo Hatsugai; Koichi Aizawa; Takahiro Inakuma; Shinji Nagata; Sho-Hei Sakuda; Hiromichi Nagasawa; Makoto Shimizu
Journal:  Br J Pharmacol       Date:  2004-09-06       Impact factor: 8.739

Review 8.  P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells.

Authors:  T Licht; I Pastan; M Gottesman; F Herrmann
Journal:  Ann Hematol       Date:  1994-10       Impact factor: 3.673

9.  Molecular analysis of the multidrug transporter, P-glycoprotein.

Authors:  U A Germann; T C Chambers
Journal:  Cytotechnology       Date:  1998-09       Impact factor: 2.058

10.  A multidrug ABC transporter with a taste for GTP.

Authors:  Cédric Orelle; Claire Durmort; Khadija Mathieu; Benjamin Duchêne; Sandrine Aros; François Fenaille; François André; Christophe Junot; Thierry Vernet; Jean-Michel Jault
Journal:  Sci Rep       Date:  2018-02-02       Impact factor: 4.379
  10 in total

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