Literature DB >> 1352229

Glucuronidation of zileuton (A-64077) by human hepatic microsomes.

D J Sweeny1, J Bouska, J Machinist, R Bell, G Carter, S Cepa, H N Nellans.   

Abstract

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Year:  1992        PMID: 1352229

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN: 0090-9556            Impact factor:   3.922


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  6 in total

1.  The effect of mild or moderate hepatic impairment (cirrhosis) on the pharmacokinetics of zileuton.

Authors:  W M Awni; J H Cavanaugh; R A Braeckman; S Y Chu; K J Patterson; J M Machinist; G R Granneman
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

2.  Pharmacokinetics and pharmacodynamics of zileuton after oral administration of single and multiple dose regimens of zileuton 600mg in healthy volunteers.

Authors:  W M Awni; R A Braeckman; G R Granneman; G Witt; L M Dubé
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

3.  Effect of zileuton on theophylline pharmacokinetics.

Authors:  G R Granneman; R A Braeckman; C S Locke; J H Cavanaugh; L M Dubé; W M Awni
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

4.  The pharmacokinetics of single oral doses of zileuton 200 to 800mg, its enantiomers, and its metabolites, in normal healthy volunteers.

Authors:  S L Wong; W M Awni; J H Cavanaugh; T el-Shourbagy; C S Locke; L M Dubé
Journal:  Clin Pharmacokinet       Date:  1995       Impact factor: 6.447

5.  The properties of A-69412: a small hydrophilic 5-lipoxygenase inhibitor.

Authors:  R L Bell; J Bouska; P R Young; C Lanni; J Machinist; P E Malo; J B Summers; D W Brooks; G W Carter
Journal:  Agents Actions       Date:  1993-03

6.  Population pharmacokinetics of zileution, a selective 5-lipoxygenase inhibitor, in patients with rheumatoid arthritis.

Authors:  W M Awni; G R Granneman; C S Locke; S R Brandwein; L M Dube
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

  6 in total

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