Literature DB >> 1352166

Rapid tranquillisation. A survey of emergency prescribing in a general psychiatric hospital.

L S Pilowsky1, H Ring, P J Shine, M Battersby, M Lader.   

Abstract

Rapid tranquillisation--giving a psychotropic to control behavioural disturbances--is common in medical practice, yet few surveys describe its use in psychiatric populations. Over five months, 102 incidents, involving 60 patients, were retrospectively surveyed. Patients most often involved were young white men. The commonest diagnosis was affective disorder (manic phase) (39%) followed by schizophrenia (33%). Fifteen patients were involved in 57% of the incidents. The majority of incidents involved injury to people or damage to property. The most frequently used drugs were diazepam and haloperidol, alone or in combination. Droperidol, chlorpromazine, sodium amytal and paraldehyde were rarely used. Diazepam alone or in combination with haloperidol delivered intravenously was most rapidly effective and was associated with greatest staff satisfaction. Serious side-effects were rare.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1352166     DOI: 10.1192/bjp.160.6.831

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  19 in total

1.  An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?

Authors:  Ramadhan Oruch; Anders Lund; Ian F Pryme; Holm Holmsen
Journal:  J Chem Biol       Date:  2010-01-27

2.  In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner.

Authors:  Ramadhan Oruch; Erlend Hodneland; Ian F Pryme; Holm Holmsen
Journal:  J Chem Biol       Date:  2009-04-30

3.  Race, quality of care, and antipsychotic prescribing practices in psychiatric emergency services.

Authors:  S P Segal; J R Bola; M A Watson
Journal:  Psychiatr Serv       Date:  1996-03       Impact factor: 3.084

Review 4.  Haloperidol plus promethazine for psychosis-induced aggression.

Authors:  Gisele Huf; Jacob Alexander; Pinky Gandhi; Michael H Allen
Journal:  Cochrane Database Syst Rev       Date:  2016-11-25

5.  Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine.

Authors: 
Journal:  BMJ       Date:  2003-09-27

Review 6.  The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements.

Authors:  Robert W Buchanan; Julie Kreyenbuhl; Deanna L Kelly; Jason M Noel; Douglas L Boggs; Bernard A Fischer; Seth Himelhoch; Beverly Fang; Eunice Peterson; Patrick R Aquino; William Keller
Journal:  Schizophr Bull       Date:  2009-12-02       Impact factor: 9.306

Review 7.  Alcohol and violence: neuropeptidergic modulation of monoamine systems.

Authors:  Klaus A Miczek; Joseph F DeBold; Lara S Hwa; Emily L Newman; Rosa M M de Almeida
Journal:  Ann N Y Acad Sci       Date:  2015-08-18       Impact factor: 5.691

8.  Rapid tranquillisation in psychiatric emergency settings in Brazil: pragmatic randomised controlled trial of intramuscular haloperidol versus intramuscular haloperidol plus promethazine.

Authors:  Gisele Huf; E S F Coutinho; C E Adams
Journal:  BMJ       Date:  2007-10-22

Review 9.  Antipsychotic-related QTc prolongation, torsade de pointes and sudden death.

Authors:  Peter M Haddad; Ian M Anderson
Journal:  Drugs       Date:  2002       Impact factor: 9.546

10.  No evidence for restrictive care practices in Măori admitted to a New Zealand psychiatric inpatient unit: do specialist cultural teams have a role?

Authors:  Shailesh Kumar; Bradley Ng; Alexander Simpson; Jesse Fischer; Elizabeth Robinson
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2008-05       Impact factor: 4.328

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.