Literature DB >> 1351481

Diagnostic confusion in treatment-refractory psychotic patients.

G N Smith1, G W MacEwan, R J Ancill, W G Honer, T S Ehmann.   

Abstract

BACKGROUND: Two surveys of diagnostic practices in the United States suggest that many clinicians base their diagnoses on presenting symptoms and pay little attention to course and exclusionary criteria. Failure to correctly diagnose patients may result in inappropriate therapy and poor treatment response. The purpose of the present study was to investigate diagnostic practices.
METHODS: We made detailed assessments of 50 consecutively admitted treatment-refractory psychotic patients and carefully applied DSM-III-R criteria.
RESULTS: Referral diagnoses were changed in 23 of the 50 patients. Diagnoses of schizophrenia and schizoaffective disorder were made far less frequently and mood disorders (bipolar disorder and major depression) were diagnosed far more frequently by our group than by referring psychiatrists. Patients whose diagnosis was changed were more likely to be given mood-stabilizing medication and tended to show more improvement than patients whose diagnosis was not changed.
CONCLUSIONS: These findings raise the possibility that patients may not respond to treatment because incorrect diagnoses result in inappropriate treatment.

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Year:  1992        PMID: 1351481

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  4 in total

Review 1.  Psychotic major depression: a benefit-risk assessment of treatment options.

Authors:  Audrey R Tyrka; Lawrence H Price; Marcelo F Mello; Andrea F Mello; Linda L Carpenter
Journal:  Drug Saf       Date:  2006       Impact factor: 5.606

2.  Symptom changes in five dimensions of the Positive and Negative Syndrome Scale in refractory psychosis.

Authors:  Todd S Woodward; Kwanghee Jung; Geoffrey N Smith; Heungsun Hwang; Alasdair M Barr; Ric M Procyshyn; Sean W Flynn; Mark van der Gaag; William G Honer
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2013-10-15       Impact factor: 5.270

3.  Depressive symptom profiles and severity patterns in outpatients with psychotic vs nonpsychotic major depression.

Authors:  Brandon A Gaudiano; Diane Young; Iwona Chelminski; Mark Zimmerman
Journal:  Compr Psychiatry       Date:  2008-03-28       Impact factor: 3.735

4.  Is schizophrenia disappearing? The rise and fall of the diagnosis of functional psychoses: an essay.

Authors:  Per Bergsholm
Journal:  BMC Psychiatry       Date:  2016-11-09       Impact factor: 3.630

  4 in total

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