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Literature DB >> 135125

[Tryptophan-load in progressive scleroderma (author's transl)].

Abstract

This presentation describes effects of oral tryptophan loading (5.0 g DL) on tryptophan metabolism in healthy subjects (n = 10) and persons with progressive scleroderma. N1-methylnicotinamide (N1MN), 3-hydroxyanthranilic acid (3 HAA), kynurine (KN), tryptamin (TA), xantheurenic acid (XA) were determinated. Alterations of tryptophan metabolism were evaluated by 24 h urinary excretions of the following metabolites: 5-hydroxy indolacetic acid (5 HAA) and indole-3-acetic acid (IAA). The pathological pathways were discussed, especially the way and influence of serotonine.

Entities: Chemical Disease Species

Mesh：

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Year: 1976 PMID： 135125 DOI： 10.1007/bf01483590

Source DB: PubMed Journal: Klin Wochenschr ISSN： 0023-2173

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References

46 in total

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Authors: G Stüttgen; E M Leipnitz; R Sya; D Ollig
Journal: Arch Klin Exp Dermatol Date: 1969

[Tryptophan-load in progressive scleroderma (author's transl)].

1. [ELECTRON MICROSCOPIC STUDIES ON THE BEHAVIOR OF COLLAGEN FIBRILS IN THE SKIN IN SCLERODERMA].

2. Dermal fibrosis following subcutaneous injections of serotonin creatinine sulphate.

3. Distribution of intracarotidly injected serotonin in the brain.

4. Association of functioning carcinoid syndrome and scleroderma. I. Case report.

6. [Determination of biogenic amines in animal and human skin as well as tumors by a thin-layer chromatographic method (Seiler technic). 3. 5-Hydroxytryptamine (serotonin)].

7. [Tryptophan metabolism in patients with pellagra].

8. Tryptophan metabolism as affected by anovulatory agents.

9. [Carcinoid tumor. Clinical aspects and therapy].

10. Metabolism of C 14 labeled enantiomers of tryptophan, kynurenine and hydroxykynurenine in humans with scleroderma.