Phenmetrazine hydrochloride; a clinical evaluation of a new anoretic agent.

Phenmetrazine hydrochloride appeared to be a safe anoretic agent and was effective in weight control in 80 per cent of a series of 49 obese patients. Tolerance to the drug did not develop in periods up to 18 weeks of continued treatment. Phenmetrazine was most effective in patients under 45 years of age in this series. Side effects were minimal and easily controlled. No allergic or toxic effects were noted.