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Literature DB >> 13489187

The concentration of adrenaline in the plasma of rabbits treated with reserpine.

Abstract

Doses of 1 to 2.3 mg./kg. of reserpine given intravenously to rabbits raised the plasma adrenaline. The noradrenaline concentrations were too near the threshold of the method to decide whether any alterations followed the injection of reserpine. Control experiments, in which blood samples were taken from rabbits but no drug was given, showed only a very slight rise in adrenaline concentration after the first bleeding.

Entities: Chemical Disease Species

Keywords: EPINEPHRINE/in blood; RESERPINE/effects

Mesh：

Substances：

Year: 1957 PMID： 13489187 PMCID： PMC1510601 DOI： 10.1111/j.1476-5381.1957.tb00178.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

10 in total

1. [Hyperglycemic effect of reserpin].

Authors: H J KUSCHKE; J FRANTZ
Journal: Naunyn Schmiedebergs Arch Exp Pathol Pharmakol Date: 1955

2. A peripheral action of reserpine.

Authors: R A MAXWELL; S D ROSS; A J PLUMMER; E B SIGG
Journal: J Pharmacol Exp Ther Date: 1957-01 Impact factor: 4.030

3. [Effect of isonicotinic acid hydrazide on the central action of reserpine and 5-hydroxytryptamine].

Authors: H BESENDORF; A PLETSCHER
Journal: Helv Physiol Pharmacol Acta Date: 1956

4. [Changes in the adrenalin and noradrenalin concentration of human blood plasma under the effects of reserpine].

Authors: M BURGER
Journal: Naunyn Schmiedebergs Arch Exp Pathol Pharmakol Date: 1957

5. Investigations into experimental hypertension. IV. The acute effects of Rauwolfia alkaloids on the blood pressure of rats with experimental renal hypertension.

Authors: D K DE JONGH; E G VAN PROOSDIJ-HARTZEMA
Journal: Acta Physiol Pharmacol Neerl Date: 1955-08

14 in total

1. The cause of the supersensitivity of smooth muscle to noradrenaline after sympathetic degeneration.

Authors: J H BURN; M J RAND
Journal: J Physiol Date: 1959-06-23 Impact factor: 5.182

2. OBSERVATIONS ON A VASOACTIVE MATERIAL IN BRAIN EXTRACTS.

Authors: T WHITE
Journal: Br J Pharmacol Chemother Date: 1964-02

3. THE EFFECT OF ADRENERGIC BLOCKING AGENTS ON THE GUINEA-PIG UTERUS IN VITRO, AND A STUDY OF THE HISTOLOGY OF THE INTRINSIC MYOMETRIAL NERVES.

Authors: P C CLEGG
Journal: J Physiol Date: 1963-11 Impact factor: 5.182

The concentration of adrenaline in the plasma of rabbits treated with reserpine.

1. [Hyperglycemic effect of reserpin].

2. A peripheral action of reserpine.

3. [Effect of isonicotinic acid hydrazide on the central action of reserpine and 5-hydroxytryptamine].

4. [Changes in the adrenalin and noradrenalin concentration of human blood plasma under the effects of reserpine].

5. Investigations into experimental hypertension. IV. The acute effects of Rauwolfia alkaloids on the blood pressure of rats with experimental renal hypertension.

6. Vasoconstrictor activity in the rabbit's blood and plasma.

7. Interaction of reserpine, serotonin, and lysergic acid diethylamide in brain.

8. The concentration of adrenaline in the peripheral blood during insulin hypoglycaemia.

9. The secretion of the denervated adrenal medulla of the cat.

10. The assay of substances from the adrenal medulla.

1. The cause of the supersensitivity of smooth muscle to noradrenaline after sympathetic degeneration.

2. OBSERVATIONS ON A VASOACTIVE MATERIAL IN BRAIN EXTRACTS.

3. THE EFFECT OF ADRENERGIC BLOCKING AGENTS ON THE GUINEA-PIG UTERUS IN VITRO, AND A STUDY OF THE HISTOLOGY OF THE INTRINSIC MYOMETRIAL NERVES.

4. [Mechanism of action of reserpine].

5. Increase in noradrenaline content of tissues after infusion of noradrenaline, dopamine and L-DOPA.

6. Peripheral effects of nicotine and acetylcholine resembling those of sympathetic stimulation.

7. The effect of precursors of noradrenalin on the response to tyramine and sympathetic stimulation.

8. The action of reserpine on the peripheral sympathetic system.

9. [Excretion of noradrenalin and adrenalin under massive reserpine therapy].

10. Noradrenaline in artery walls and its dispersal by reserpine.