Literature DB >> 13489163

Susceptibility of certain enzymes of the central nervous system to tetrodotoxin.

K KURIAKI, H NAGANO.   

Abstract

The neurotoxic poison from the roe of Fugu, a globe fish living in the waters of Japan, was investigated with reference to its effect on the main oxidation-reduction systems, acetyl-cholinesterase and choline-acetylase in the brain of the guinea-pig.It was found that the poison inhibited the choline-acetylase activity, even in a concentration of 4.4x10(-7). Acetyl-cholinesterase and cytochrome-c-oxidase activities were also inhibited in concentration of 1.3x10(-5) and 0.8x10(-5) respectively.

Entities:  

Keywords:  BRAIN/metabolism; CHOLINESTERASE/antagonists; ESTERASES; OXIDASES; POISONS

Mesh：

Substances：

Year:  1957        PMID： 13489163      PMCID： PMC1510577          DOI： 10.1111/j.1476-5381.1957.tb00154.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  9 in total

1.  [Paper chromatographic separation of acid-soluble phosphorus compounds from renal tissues].

Authors:  E GERLACH; E WEBER
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1955

2.  Effect of Fugu poison on reflex activities.

Authors:  K KURIAKI; K HIYOSHI; Y MOCHIZUKI
Journal:  Jpn J Pharmacol       Date:  1956-09

3.  The action of botulinum toxin on motor-nerve filaments.

Authors:  V B BROOKS
Journal:  J Physiol       Date:  1954-03-29       Impact factor: 5.182

4.  [Paper chromatographic separation of ATP, ADP and other phosphorus compounds in contracted and relaxed frog muscle].

Authors:  A FLECKENSTEIN; J JANKE
Journal:  Pflugers Arch Gesamte Physiol Menschen Tiere       Date:  1953

5.  The beta-hydroxybutyric dehydrogenase of animal tissues.

Authors:  D E Green; J G Dewan; L F Leloir
Journal:  Biochem J       Date:  1937-06       Impact factor: 3.857

6.  An improved method for the colorimetric determination of phosphate.

Authors:  I Berenblum; E Chain
Journal:  Biochem J       Date:  1938-02       Impact factor: 3.857

7.  The peripheral action of Cl. botulinum toxin.

Authors:  N Ambache
Journal:  J Physiol       Date:  1949-03-15       Impact factor: 5.182

8.  [Mechanism of action of venoms].

Authors:  A FLECKENSTEIN
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1952

9.  The action of botulinum toxin on the neuro-muscular junction.

Authors:  A S V BURGEN; F DICKENS; L J ZATMAN
Journal:  J Physiol       Date:  1949-08       Impact factor: 5.182
  9 in total
  2 in total

1.  Intracellular distributions of acetylcholine and choline acetylase.

Authors:  C O HEBB; V P WHITTAKER
Journal:  J Physiol       Date:  1958-06-18       Impact factor: 5.182

2.  Components of O2-uptake by excised frog nerve dependent upon externally supplied sodium ions.

Authors:  F Brink
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.