Literature DB >> 13481248

The influence of cortisone on experimental viral infection. IIL Effects on certain dynamics of influenza virus increase.

E D KILBOURNE.   

Abstract

The administration of cortisone to chicken embryos infected with influenza B virus results in (a) an initial inhibition of viral synthesis and (b) an eventual increase in the final yield of virus attained. Increased yields of virus are attained regardless of the number of viral particles in the infecting inoculum or the proportion of particles which are infective. Changes in the distribution ratios of allantoic fluid and intramembrane virus are effected by cortisone only as the secondary result of reduction in viral synthesis. The manifest effect of cortisone on influenza A virus increase is inhibitory unless inocula containing relatively high proportions of inactive viral particles are used.

Entities:  

Keywords:  CORTISONE/effects; INFLUENZA VIRUSES/effect of drugs on

Mesh：

Substances：

Year:  1957        PMID： 13481248      PMCID： PMC2136830          DOI： 10.1084/jem.106.6.851

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  13 in total

1.  The number of allantoic cells in the chick embryo.

Authors:  H J CAIRNS; S FAZEKAS DE ST. GROTH
Journal:  J Immunol       Date:  1957-03       Impact factor: 5.422

2.  Fractional dilution procedure for precise titration of hemagglutinating viruses and hemagglutination-inhibiting antibodies.

Authors:  F L HORSFALL; I TAMM
Journal:  J Immunol       Date:  1953-03       Impact factor: 5.422

3.  In vitro effects of cortisone on multiplication of influenza B virus.

Authors:  E D KILBOURNE; I TATENO
Journal:  Proc Soc Exp Biol Med       Date:  1953-02

4.  Interference in cortisone-treated hosts.

Authors:  J FONG; R LOUIE
Journal:  Proc Soc Exp Biol Med       Date:  1953-11

5.  A new count of allontoic cells of the 10-day chick embryo.

Authors:  D A TYRRELL; I TAMM; O C FORSSMAN; F L HORSFALL
Journal:  Proc Soc Exp Biol Med       Date:  1954-07

6.  The influence of cortisone on experimental viral infection. IV. Negation of interference as the mechanism by which cortisone induces increased virus yields.

Authors:  E D KILBOURNE
Journal:  J Exp Med       Date:  1957-12-01       Impact factor: 14.307

7.  On the reproduction of influenza virus; quantitative studies with procedures which enumerate infective and hemagglutinating virus particles.

Authors:  F L HORSFALL
Journal:  J Exp Med       Date:  1954-08-01       Impact factor: 14.307

8.  Reproduction of influenza viruses; quantitative investigations with particle enumeration procedures on the dynamics of influenza A and B virus reproduction.

Authors:  F L HORSFALL
Journal:  J Exp Med       Date:  1955-10-01       Impact factor: 14.307

9.  Influenza virus and its mucoprotein substrate in the chorioallantoic membrane of the chick embryo. II. Stepwise inactivation of substrate and its relation to the mode of viral multiplication.

Authors:  R W SCHLESINGER; H V KARR
Journal:  J Exp Med       Date:  1956-03-01       Impact factor: 14.307

10.  The effect of adrenal steroids, corticotropin, and growth hormone on resistance to experimental infections.

Authors:  E H KASS; M M LUNDGREN; M FINLAND
Journal:  J Exp Med       Date:  1954-01-01       Impact factor: 14.307
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  12 in total

1.  [Experimental studies on the nature of cortisone action in virus infections with special reference to the interference mechanism].

Authors:  G THIELE; H STAUTER
Journal:  Z Hyg Infektionskr       Date:  1961

2.  Effect of cortisone on the growth of psittacosis virus in cultures of L cells.

Authors:  R B STEWART
Journal:  J Bacteriol       Date:  1960-07       Impact factor: 3.490

3.  Cell metabolism and virus.

Authors:  E KOVACS
Journal:  Experientia       Date:  1961-04-15

4.  [Mechanisms of nonspecific infection resistance].

Authors:  D BOHME
Journal:  Klin Wochenschr       Date:  1958-09-15

5.  Effect of triiodothyronine on cells and on their response to infection by polioviruses.

Authors:  W H MURPHY; C BULLIS
Journal:  J Bacteriol       Date:  1962-03       Impact factor: 3.490

6.  Effect of "Aquasol A", vitamin A, and "Tween 80" on vesicular stomatitis virus plaque formation and on interferon action.

Authors:  J E Blalock; G E Gifford
Journal:  Arch Gesamte Virusforsch       Date:  1974

7.  Presentation of Academy Medal to Edwin D. Kilbourne, M.D.

Authors:  G K Hirst
Journal:  Bull N Y Acad Med       Date:  1983-09

8.  Some aspects of plaque formation by human influenza viruses. I. Cell and media factors affecting a modified plaque technique.

Authors:  C P De Sousa; G Belyavin
Journal:  Arch Gesamte Virusforsch       Date:  1970

9.  The influence of cortisone on experimental viral infection. VII. Kinetics of interferon formation and its inhibition with hydrocortisone in relation to viral strain and virulence.

Authors:  K M Smart; E D Kilbourne
Journal:  J Exp Med       Date:  1966-02-01       Impact factor: 14.307

10.  The influence of cortisone on experimental viral infection. IV. Negation of interference as the mechanism by which cortisone induces increased virus yields.

Authors:  E D KILBOURNE
Journal:  J Exp Med       Date:  1957-12-01       Impact factor: 14.307
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