| Literature DB >> 1348056 |
E S Bochkareva1, N M Lissin, G C Flynn, J E Rothman, A S Girshovich.
Abstract
In the presence of its partner, GroES, the tetradecameric molecular chaperone GroEL binds 14 ATP molecules, half of which are hydrolyzed in a cooperative manner. Moreover GroEL can bind, with a positive cooperativity, more than two molecules of nonfolded protein rhodanese. The role of the cooperative mechanism in the functioning of GroEL is discussed.Entities:
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Year: 1992 PMID： 1348056
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157