Literature DB >> 1346751

The presence of free D-alanine, D-proline and D-serine in mice.

Y Nagata1, K Yamamoto, T Shimojo, R Konno, Y Yasumura, T Akino.   

Abstract

The presence of free D-alanine, D-proline and D-serine was demonstrated in mammalian tissues, using a mutant mouse strain lacking D-amino acid oxidase. In the experiment, free amino acids from the kidney and serum were derivatized with 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (FDAA) to diastereomers, separated by two-dimensional thin-layer chromatography (TLC), and analysed by reversed-phase high-performance liquid chromatography (HPLC) for the resolution of D- and L-isomers. D/L ratios of alanine, proline and serine were obtained based on the peak areas of HPLC.

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Year:  1992        PMID： 1346751     DOI： 10.1016/0304-4165(92)90055-y

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  D-Aspartyl residue in a peptide can be liberated and metabolized by pig kidney enzymes.

Authors:  Y Kera; K Funabashi; T Matsumoto; T Watanabe; H Nagasaki; R Yamada
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

2.  D-aspartate localizations imply neuronal and neuroendocrine roles.

Authors:  M J Schell; O B Cooper; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

Review 3.  Metabolism of the neuromodulator D-serine.

Authors:  Loredano Pollegioni; Silvia Sacchi
Journal:  Cell Mol Life Sci       Date:  2010-03-02       Impact factor: 9.261

4.  Involvement of D-amino acid oxidase in elimination of D-serine in mouse brain.

Authors:  Y Nagata
Journal:  Experientia       Date:  1992-08-15

Review 5.  The neurobiology of D-amino acid oxidase and its involvement in schizophrenia.

Authors:  L Verrall; P W J Burnet; J F Betts; P J Harrison
Journal:  Mol Psychiatry       Date:  2009-09-29       Impact factor: 15.992

6.  A trial to determine D-amino acids in tissue proteins of mice.

Authors:  Y Nagata; K Kubota
Journal:  Amino Acids       Date:  1993-02       Impact factor: 3.520

7.  Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker.

Authors:  Sheryl L W Zajdowicz; Jessica Jones-Carson; Andres Vazquez-Torres; Michael G Jobling; Ronald E Gill; Randall K Holmes
Journal:  PLoS One       Date:  2011-06-24       Impact factor: 3.240

Review 8.  Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.

Authors:  Reiko Koga; Yurika Miyoshi; Hiroaki Sakaue; Kenji Hamase; Ryuichi Konno
Journal:  Front Mol Biosci       Date:  2017-12-04

9.  Principles of protein targeting to the nucleolus.

Authors:  Robert M Martin; Gohar Ter-Avetisyan; Henry D Herce; Anne K Ludwig; Gisela Lättig-Tünnemann; M Cristina Cardoso
Journal:  Nucleus       Date:  2015       Impact factor: 4.197
  9 in total

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