Literature DB >> 13463274

The proportion of terramycin-resistant mutants in B. megatherium cultures.

J H NORTHROP.   

Abstract

The number of terramycin-resistant mutants in Bacillus megatherium cultures, their mutation rate, and the growth rate of the wild and mutant cells have been determined under various conditions. These values are in agreement with the following equations (Northrop and Kunitz, 1957):- See PDF for Equation lambda = mutation rate, A = growth rate constant of wild cells, B = growth rate constant of mutants, See PDF for Equation equilibrium. The value of the mutation rate as determined from equation (6) agrees with that found by the null fraction method.

Entities:  

Keywords:  BACILLUS MEGATERIUM/culture; OXYTETRACYCLINE/effects

Mesh:

Substances:

Year:  1957        PMID: 13463274      PMCID: PMC2194818          DOI: 10.1085/jgp.41.1.131

Source DB:  PubMed          Journal:  J Gen Physiol        ISSN: 0022-1295            Impact factor:   4.086


  5 in total

1.  Experiments on spontaneous and chemically induced mutations of bacteria growing in the Chemostat.

Authors:  A NOVICK; L SZILARD
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1951

2.  The effect of ultraviolet and white light on growth rate, lysis, and phage production of Bacillus megatherium.

Authors:  J H NORTHROP
Journal:  J Gen Physiol       Date:  1957-05-20       Impact factor: 4.086

3.  Growth and phage production of B. megatherium. I. Growth of cells after infection with C phage. II. Rate of growth, phage yield, and RNA content of cells. III. Effect of various substances on growth rate and phage production.

Authors:  J H NORTHROP
Journal:  J Gen Physiol       Date:  1953-03       Impact factor: 4.086

4.  The proportion of mutants in bacterial cultures.

Authors:  J H NORTHROP; M KUNITZ
Journal:  J Gen Physiol       Date:  1957-09-20       Impact factor: 4.086

5.  Appearance of new phage types and new lysogenic strains after adaptation of lysogenic B. megatherium to ammonium sulfate culture medium.

Authors:  J H NORTHROP; J S MURPHY
Journal:  J Gen Physiol       Date:  1956-03-20       Impact factor: 4.086

  5 in total
  6 in total

1.  CONCERNING THE ORIGIN OF BACTERIAL VIRUSES.

Authors:  J H Northrop
Journal:  Proc Natl Acad Sci U S A       Date:  1958-03       Impact factor: 11.205

2.  Apparatus for the Maintenance of Bacterial Cultures in the Steady State : II. Improved turbidity control and culture cell.

Authors:  J H Northrop
Journal:  J Gen Physiol       Date:  1960-01-01       Impact factor: 4.086

3.  Increased mutation rate of E. coli K12 lambda cultures maintained in continuous logarithmic growth.

Authors:  J H Northrop
Journal:  J Gen Physiol       Date:  1966-11       Impact factor: 4.086

4.  Studies on the origin of bacterial viruses. V. The effect of temperature on the terramycin-resistant and phage-producing cells of Bacillus megatherium cultures.

Authors:  J H NORTHROP
Journal:  J Gen Physiol       Date:  1958-11-20       Impact factor: 4.086

5.  Studies on the origin of bacterial viruses. I-IV.

Authors:  J H NORTHROP
Journal:  J Gen Physiol       Date:  1958-09-20       Impact factor: 4.086

6.  Studies of the origin of bacterial viruses. VI. Effect of manganese on the proportion of phage-producing. terramycin-resistant, streptomycin-resistant, and phage-resistant cells in lysogenic megatherium cultures.

Authors:  J H NORTHROP
Journal:  J Gen Physiol       Date:  1960-01       Impact factor: 4.086

  6 in total

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