| Literature DB >> 134546 |
E P Rieber, J G Saal, G Riethmüller, H W Heyden, H D Waller.
Abstract
The neoplastic cells of a patient with hairy cell leukemia were found to express a high Fc-receptor actitivy on their surface. When the Fc-receptors were determined quantitatively by measuring the uptake of 125I-labelled aggregated IgG under saturation conditions, it was found that the hariy cells bound approximately 3 times more aggregated IgG than normal adherent mononuclear cells. The bound 125I-Agg. IgG was evenly distributed on the cell surface when the cells were labelled at 4 degrees C and was rapidly redistributed in form of a cap at one cell pole during incubation at 20 degrees C.Entities:
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Year: 1976 PMID： 134546
Source DB: PubMed Journal: Z Immunitatsforsch Exp Klin Immunol ISSN： 0300-872X