Literature DB >> 1345302

[The oral route: an access port for Trypanosoma cruzi].

M L Calvo Méndez1, B Nogueda Torres, R Alejandre Aguilar.   

Abstract

Rats and mice were inoculated by oral route with T. cruzi from: 1. Infected mice blood, 2. Experimentally infected triatomines feces, 3. Experimentally infected alive triatomines, and 4. Free cell cultures. Mice showed to be more susceptible to the infection than rats. Mice exhibited to be infected: 30% with blood forms, 85% with triatomines feces, 75% with alive triatomines and 35% with culture forms. Rats exhibited to be infected: 10%, with blood forms, 45% with triatomines feces, 60% with alive triatomines and 25% with culture forms. In both species we observed that metacyclic trypomastigotes originated higher infection percentage than blood and culture forms. With these results we confirm that oral route is a probable way of transmission of T. cruzi and under standardized conditions, it represents a better experimental inoculation route than intraperitoneal route.

Entities:  

Mesh:

Year:  1992        PMID: 1345302

Source DB:  PubMed          Journal:  Rev Latinoam Microbiol        ISSN: 0187-4640


  6 in total

1.  Type 1 immunity provides optimal protection against both mucosal and systemic Trypanosoma cruzi challenges.

Authors:  D F Hoft; C S Eickhoff
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

2.  Natural Chagas disease in four baboons.

Authors:  Jeff T Williams; Edward J Dick; John L VandeBerg; Gene B Hubbard
Journal:  J Med Primatol       Date:  2008-07-30       Impact factor: 0.667

3.  Polymerase chain reaction detection of Trypanosoma cruzi in Macaca fascicularis using archived tissues.

Authors:  Jeff T Williams; James N Mubiru; Natalia E Schlabritz-Loutsevitch; Rohina C Rubicz; John L VandeBerg; Edward J Dick; Gene B Hubbard
Journal:  Am J Trop Med Hyg       Date:  2009-08       Impact factor: 2.345

4.  Anatomical route of invasion and protective mucosal immunity in Trypanosoma cruzi conjunctival infection.

Authors:  O K Giddings; C S Eickhoff; T J Smith; L A Bryant; D F Hoft
Journal:  Infect Immun       Date:  2006-10       Impact factor: 3.441

5.  Gastric invasion by Trypanosoma cruzi and induction of protective mucosal immune responses.

Authors:  D F Hoft; P L Farrar; K Kratz-Owens; D Shaffer
Journal:  Infect Immun       Date:  1996-09       Impact factor: 3.441

6.  Oral transmission of Trypanosoma cruzi with opposing evidence for the theory of carnivory.

Authors:  Dawn M Roellig; Angela E Ellis; Michael J Yabsley
Journal:  J Parasitol       Date:  2009-04       Impact factor: 1.276

  6 in total

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